Title:
ANTI-CANINE PD-1 ANTIBODY OR ANTI-CANINE PD-L1 ANTIBODY
Document Type and Number:
WIPO Patent Application WO/2016/006241
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing: an anti-canine PD-1 antibody or an anti-canine PD-L1 antibody; an agent for inhibiting binding of canine PD-1 and canine PD-L1 that contains said antibody; a method for inhibiting binding of canine PD-1 and canine PD-L1 that uses said antibody; and a gene that codes said antibody. An anti-canine PD-1 antibody that binds specifically to canine PD-1 comprising an amino acid sequence represented by SEQ ID NO: 1 or an anti-canine PD-L1 antibody that binds specifically to canine PD-L1 comprising an amino acid sequence represented by SEQ ID NO: 6 are produced. Furthermore, an agent for inhibiting binding of canine PD-1 and canine PD-L1 that contains said antibody is produced.
Inventors:
MIZUNO TAKUYA (JP)
SHOSU KAZUHA (JP)
SHOSU KAZUHA (JP)
Application Number:
PCT/JP2015/003444
Publication Date:
January 14, 2016
Filing Date:
July 08, 2015
Export Citation:
Assignee:
NIPPON ZENYAKU KOGYO CO LTD (JP)
International Classes:
C07K16/28; A61K39/395; A61P35/00; C07K16/18; C12N15/09
Domestic Patent References:
| WO2013173223A1 | 2013-11-21 |
Other References:
MEAEKAWA ET AL.: "Expression of PD-L1 on canine tumor cells and enhancement of IFN-gamma production from tumor-infiltrating cells by PD-L1 blockade", PLOS ONE, vol. 9, no. Issue 6, June 2014 (2014-06-01), pages e98415, XP055179324
See also references of EP 3168236A4
See also references of EP 3168236A4
Attorney, Agent or Firm:
HIROTA, Masanori (JP)
Masaki Hirota (JP)
Masaki Hirota (JP)
Download PDF:
Previous Patent: AIR SPINNING DEVICE AND SPINNING MACHINE
Next Patent: FILTER FAILURE DIAGNOSTIC DEVICE FOR AN INTERNAL COMBUSTION ENGINE
Next Patent: FILTER FAILURE DIAGNOSTIC DEVICE FOR AN INTERNAL COMBUSTION ENGINE