ANTI-LIV-1 ANTIBODY, DRUG CONJUGATE THEREOF, AND MEDICAL USE THEREOF

Title:

ANTI-LIV-1 ANTIBODY, DRUG CONJUGATE THEREOF, AND MEDICAL USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2024/109944

Kind Code:

A1

Abstract:

Provided are a LIV-1 binding molecule and a preparation method therefor, and a corresponding immunoconjugate, a pharmaceutical composition, a medical use, and a method for preventing a disease, in particular a method for treating cancer or a tumor.

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Inventors:

DONG LIWEI (CN)
ZHANG WEI (CN)
CHEN SIMENG (CN)
WANG LILI (CN)
LIAO CHENG (CN)

Application Number:

PCT/CN2023/134161

Publication Date:

May 30, 2024

Filing Date:

November 24, 2023

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Assignee:

JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN)
SHANGHAI SHENGDI PHARMACEUTICAL CO LTD (CN)

International Classes:

A61K39/395; C07K16/28; A61P35/00; C07K16/30; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12N15/13; C12N15/63

Foreign References:

CN103533957A	2014-01-22
CN106999517A	2017-08-01
CN114206933A	2022-03-18
CN1849337A	2006-10-18
US20040141983A1	2004-07-22
US20050175619A1	2005-08-11

Attorney, Agent or Firm:

GE CHENG & CO., LTD (CN)

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