Title:
ANTI-TORCH-IGG ANTIBODY PROFILE CHIP AND PREPARATION METHOD THEREFOR, AND TORCH DETECTION KIT
Document Type and Number:
WIPO Patent Application WO/2019/169796
Kind Code:
A1
Abstract:
The present invention relates to the technical field of biological detection, and provides an anti-torch-IgG antibody profile chip and a preparation method therefor, and a TORCH detection kit and a detection method. The anti-torch-IgG antibody profile chip can be used for simultaneously and quantitatively detecting the infection of related pathogenic microbes of TORCH. Moreover, by optimizing coating liquid and coating conditions of the chip and sealing stabilizing agents, the stability of the anti-torch-IgG antibody profile chip is better, and the service cycle is longer. The TORCH detection kit provided by the present invention has the advantages that the consumption of relevant antigens can be effectively reduced, the antigen cost can be reduced, and meanwhile, the stable period is longer, the use period is longer, the transportation cost is reduced, and the storage and transportation convenience is improved. The TORCH detection method can be used for simultaneously and quantitatively detecting the infection of various related pathogenic microbes of TORCH, the sensitivity is high, and the specificity is high.
Inventors:
ZHANG DAZHUN (CN)
XIAO CHUAN (CN)
ZHANG YONGDING (CN)
MA WEIMIN (CN)
WANG HONGTAO (CN)
MA XINMIN (CN)
XIAO CHUAN (CN)
ZHANG YONGDING (CN)
MA WEIMIN (CN)
WANG HONGTAO (CN)
MA XINMIN (CN)
Application Number:
PCT/CN2018/092845
Publication Date:
September 12, 2019
Filing Date:
June 26, 2018
Export Citation:
Assignee:
SHENZHEN BLOT BIOTECH CO LTD (CN)
International Classes:
G01N33/68
Other References:
LIANG, RUQIANG: "microRNA (Part I: Construction of Protein Microarray Platform and TORCH Antigen Microarray; Part II: A Novel MicroRNA Profiling Microarray; Part III: Conformation and Unfolding of Leucyl-tRNA Synthetase of Aquifex Aeolicus", DOCTORAL DISSERTATION OF GRADUATE UNIVERSITY OF CHINESE ACADEMY OF SCIENCES, 31 January 2007 (2007-01-31)
GE, HAIPENG ET AL.: "Simultaneous Multianalyte Protein Microarray for Detection of Anti-ToRCH Antibodies in Human Serum", CHINESE JOURNAL OF IMMUNOLOGY, vol. 22, no. 2, 31 December 2006 (2006-12-31), pages 161 - 164,167
ZHANG, QIAN E: "Preliminary Study in Preparation of TORCH Antigen Microarray Using Fluorescence Detection in Perinatal Period", THESIS, 31 January 2007 (2007-01-31), Southeast University
GE, HAIPENG ET AL.: "Simultaneous Multianalyte Protein Microarray for Detection of Anti-ToRCH Antibodies in Human Serum", CHINESE JOURNAL OF IMMUNOLOGY, vol. 22, no. 2, 31 December 2006 (2006-12-31), pages 161 - 164,167
ZHANG, QIAN E: "Preliminary Study in Preparation of TORCH Antigen Microarray Using Fluorescence Detection in Perinatal Period", THESIS, 31 January 2007 (2007-01-31), Southeast University
Attorney, Agent or Firm:
SHENPAT INTELLECTUAL PROPERTY AGENCY (CN)
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