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Title:
ANTIDRUG ANTIBODY MEASUREMENT METHOD
Document Type and Number:
WIPO Patent Application WO/2022/210066
Kind Code:
A1
Abstract:
Provided is a measurement method for antidrug antibodies that is easier and lower-cost compared with conventional methods. Provided is a double antigen bridging immunoassay method using a capture nucleic acid and a tracer nucleic acid. By using the capture nucleic acid and the tracer nucleic acid in the double antigen bridging immunoassay method, it is possible to measure antidrug antibodies easily and at a lower cost. Moreover, by using the tracer nucleic acid, it becomes possible to employ a nucleic acid–utilizing high-sensitivity detection method.

Inventors:
SEKINO TETSUO (JP)
OOMORI AKANE (JP)
Application Number:
PCT/JP2022/012965
Publication Date:
October 06, 2022
Filing Date:
March 22, 2022
Export Citation:
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Assignee:
SEKISUI MEDICAL CO LTD (JP)
International Classes:
C12Q1/68; G01N33/53
Domestic Patent References:
WO2013172305A12013-11-21
WO2013172305A12013-11-21
Foreign References:
US20170044591A12017-02-16
JP6718032B12020-07-08
JP4902674B22012-03-21
US20150226758A12015-08-13
JP4902674B22012-03-21
JP3267576B22002-03-18
Other References:
ALEXANDER BUHL, JOCHEN H. METZGER, NIELS H. H. HEEGAARD, PHILIPP VON LANDENBERG, MARTIN FLECK, PETER B. LUPPA: "Novel Biosensor–Based Analytic Device for the Detection of Anti–Double-Stranded DNA Antibodies", CLINICAL CHEMISTRY, AMERICAN SOCIETY FOR CLINICAL PATHOLOGY, US, vol. 53, no. 2, 1 February 2007 (2007-02-01), US , pages 334 - 341, XP002519232, ISSN: 1056-599X, DOI: 10.1373/clinchem.2006.077339
HASEGAWA, ANAL SCI, vol. 32, no. 6, 2016, pages 603 - 6
Attorney, Agent or Firm:
MOEGI PATENT OFFICE (JP)
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