Title:
ANTIGEN-BINDING PROTEINS TARGETING SHARED NEOANTIGENS
Document Type and Number:
WIPO Patent Application WO/2021/097365
Kind Code:
A3
Abstract:
Provided herein are target HLA-PEPTIDE antigens, e.g., HLA-PEPTIDE neoantigens and shared tumor HLA-PEPTIDE antigens, and antigen binding proteins (ABPs) that bind the target HLA- PEPTIDE antigens. Also disclosed are methods for identifying target HLA-PEPTIDE antigens as well as identifying one or more antigen binding proteins that bind a given HLA-PEPTIDE target antigen.
Inventors:
JOOSS KARIN (US)
NOWICKA ALEKSANDRA (US)
JALLOH ABUBAKAR (US)
YELENSKY ROMAN (US)
SUN JAMES (US)
BUSBY JENNIFER (US)
DAVIS MATTHEW (US)
NOWICKA ALEKSANDRA (US)
JALLOH ABUBAKAR (US)
YELENSKY ROMAN (US)
SUN JAMES (US)
BUSBY JENNIFER (US)
DAVIS MATTHEW (US)
Application Number:
PCT/US2020/060605
Publication Date:
July 08, 2021
Filing Date:
November 13, 2020
Export Citation:
Assignee:
GRITSTONE BIO INC (US)
International Classes:
C07K16/28; A61K39/39; A61K48/00; A61P35/00; A61P43/00
Domestic Patent References:
| WO2019036688A1 | 2019-02-21 |
Other References:
DATABASE UniProtKB [online] 13 November 2019 (2019-11-13), "Uncharacterized protein", XP055838950, Database accession no. A0A0R2NH05_9LACO
DATABASE UniProtKB [online] 16 October 2019 (2019-10-16), "Processed cyclic AMP-responsive element-binding protein 3-like protein 1", XP055838953, Database accession no. Q96 BA 8
DATABASE UniProtKB [online] 16 October 2019 (2019-10-16), "Processed cyclic AMP-responsive element-binding protein 3-like protein 1", XP055838953, Database accession no. Q96 BA 8
Attorney, Agent or Firm:
NEWMAN, Zachary, R. et al. (US)
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