Title:
ANTIMICROBIAL CATIONIC PEPTIDES
Document Type and Number:
WIPO Patent Application WO1996038473
Kind Code:
A3
Abstract:
A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include NH2-KWKSFIKKLTTAVKKVLTTGLPALIS-COOH (SEQ ID NO:1) and NH2-KWKSFIKKLTSAAKKVVTTAKPLISS-COOH (SEQ ID NO:2).
Inventors:
HANCOCK ROBERT E W
KARUNARTNE NEDRA
KARUNARTNE NEDRA
Application Number:
PCT/IB1996/000589
Publication Date:
April 03, 1997
Filing Date:
May 31, 1996
Export Citation:
Assignee:
UNIV BRITISH COLUMBIA (CA)
International Classes:
A01N37/20; A61K31/43; A61K31/545; A61K31/65; A61K31/70; C12N15/09; A61K38/00; A61K38/16; A61P31/04; A61P31/10; A61P39/02; C07K7/08; C07K14/00; C07K14/435; (IPC1-7): C07K14/00; C07K7/08; C12N15/11; A61K38/16; A61K38/10
Domestic Patent References:
| WO1994004688A2 | 1994-03-03 | |||
| WO1990012866A1 | 1990-11-01 | |||
| WO1994028921A1 | 1994-12-22 | |||
| WO1995008560A1 | 1995-03-30 |
Other References:
K.L.PIERS E.A.: "The interaction of a recombinant cecropin/melittin hybrid peptide with the outer membrane of P.aeruginosa", MOL.MICROBIOL., vol. 12, no. 6, 1994, pages 951 - 958, XP000611520
R.BESSALLE E.A.: "Structure-function studies of amphiphilic antibacterial peptides", JOURNAL OF MEDICINAL CHEMISTRY, vol. 36, no. 9, 1993, WASHINGTON US, pages 1203 - 1209, XP002024716
R.BESSALLE E.A.: "Structure-function studies of amphiphilic antibacterial peptides", JOURNAL OF MEDICINAL CHEMISTRY, vol. 36, no. 9, 1993, WASHINGTON US, pages 1203 - 1209, XP002024716
Download PDF: