Title:
APPARATUS AND METHOD FOR TESTING MULTI-FUNCTION AND DRUG RESPONSE OF CENTRIFUGAL MICROFLUIDICS-BASED PLATELETS
Document Type and Number:
WIPO Patent Application WO/2014/104807
Kind Code:
A1
Abstract:
The present invention relates to an apparatus and method for testing multi-function and drug response of centrifugal microfluidics-based platelets. The testing apparatus according to the present invention may include: a rotatable disk; a sample chamber arranged at the center of the disk such that a blood sample is accommodated therein; stirring chambers respectively connected to the sample chamber in multiple radial directions so as to introduce a shear flow in the blood sample; microchannels connected to the stirring chambers such that adhesion and cohesion of platelets occur during the movement of the blood sample; and a waste sample chamber in which the blood sample is accommodated after passing through the microchannels. According to the present invention, multiple drug tests can be performed on a single blood sample at one time in multiple channels such that multiple tests is possible with respect to complex platelet functions, and thus testing time is reduced and testing costs can be saved.
Inventors:
SHIN SE HYUN (KR)
LIM CHAE SEUNG (KR)
NAM JEONG HOON (KR)
LIM HYUN JUNG (KR)
LIM CHAE SEUNG (KR)
NAM JEONG HOON (KR)
LIM HYUN JUNG (KR)
Application Number:
PCT/KR2013/012289
Publication Date:
July 03, 2014
Filing Date:
December 27, 2013
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
G01N33/49; G01N33/15; G01N35/08
Foreign References:
| KR101193566B1 | 2012-10-22 | |||
| KR20110056168A | 2011-05-26 | |||
| US20120301966A1 | 2012-11-29 | |||
| US20100099130A1 | 2010-04-22 | |||
| US20110223627A1 | 2011-09-15 |
Other References:
JEON, H. J. ET AL.: "Shear-dependent platelet function analysis with a disposable microchip", KSME, JOURNAL OF 2012 FALL CONFERENCE, November 2012 (2012-11-01), pages 676 - 679, XP008180608
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
특허법인 다나 (KR)
특허법인 다나 (KR)
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