Title:
APTAMER SPECIFICALLY BINDING TO CANCER STEM CELLS, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/197352
Kind Code:
A1
Abstract:
The present invention relates to an aptamer that specifically binds to cancer stem cells. An aptamer according to the present invention specifically binds to cancer stem cells and reduces cell adhesion, cell proliferation, anti-cancer agent resistance and cell migration, which are characteristics of cancer stem cells, thus having excellent anti-cancer effects. Therefore, the aptamer can be used in various ways in the fields of cancer diagnosis, prognosis, and treatment.
Inventors:
KIM JAE HO (KR)
KIM DAE KYOUNG (KR)
KIM DAE KYOUNG (KR)
Application Number:
PCT/KR2020/004329
Publication Date:
October 01, 2020
Filing Date:
March 30, 2020
Export Citation:
Assignee:
NAT UNIV PUSAN IND UNIV COOP FOUND (KR)
International Classes:
C12N15/115; A23L33/10; A61K31/7088; A61K47/54; A61P35/00; C12Q1/6886; G01N33/53; G01N33/574
Foreign References:
| KR20150085806A | 2015-07-24 | |||
| KR20180010203A | 2018-01-30 | |||
| KR20160029335A | 2016-03-15 | |||
| KR20140021973A | 2014-02-21 |
Other References:
HAN, ARYEO ET AL.: "Development of CD 166 Aptamer f'or Targeting Ovarian Cancer Stem-Like Celis", MASTER'S THESIS, pages 1 - 43
STEM CELLS, vol. 34, 2016, pages 551 - 564
STEM CELLS, vol. 34, 2016, pages 551 - 564
Attorney, Agent or Firm:
KIM, Soon Woong (KR)
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