Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
AROMATIC THIOETHER LIVER X-RECEPTOR MODULATORS
Document Type and Number:
WIPO Patent Application WO2003059874
Kind Code:
A3
Abstract:
The present invention is directed to selective LXR modulators, small molecule compounds corresponding to Formula (I) and is further directed to a process of treating a condition in a mammal that is modulated by LXR using a therapeutically effective dose of a compound of Formula (I).

Inventors:
CHANDRAKUMAR NIZAL S (US)
DALTON CHRISTOPHER R (US)
MALECHA JAMES W (US)
TOLLEFSON MICHAEL B (US)
VANCAMP JENNIFER ANN (US)
COX PHILLIP B (US)
Application Number:
PCT/US2002/041083
Publication Date:
April 01, 2004
Filing Date:
December 23, 2002
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
PHARMACIA CORP (US)
CHANDRAKUMAR NIZAL S (US)
DALTON CHRISTOPHER R (US)
MALECHA JAMES W (US)
TOLLEFSON MICHAEL B (US)
VANCAMP JENNIFER ANN (US)
COX PHILLIP B (US)
International Classes:
A61K31/167; A61K31/352; A61K31/357; A61K31/36; A61K31/366; A61K31/381; A61K31/4402; A61P1/16; A61P3/06; A61P3/10; A61P9/10; A61P25/28; A61P43/00; C07C323/41; C07C323/42; C07D213/32; C07D311/08; C07D311/16; C07D317/56; C07D317/62; C07D317/64; C07D319/08; C07D333/38; C07D333/40; C07D407/12; C07D409/12; (IPC1-7): C07D409/12; C07D333/38; C07D317/62; C07D319/08; C07D311/16; C07C323/41; C07D407/12; C07C323/42; C07D317/56; C07D213/32; C07D317/64; A61K31/167; A61K31/357; A61K31/36; A61K31/381
Domestic Patent References:
WO2001060818A12001-08-23
WO2002046181A22002-06-13
Foreign References:
US3378586A1968-04-16
US5690904A1997-11-25
EP0453658A21991-10-30
Other References:
H. OKAMOTO ETAL, NATURE, vol. 406, no. 6792, 2000, pages 203 - 207, XP002266120
"Chemical Abstracts Service Registry Handbook, 2000 Supplement; ISSN: 0093-058X; CAS Registry Number 256285-97-9 through 260528-41-4", 2000, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, XP002266173
DATABASE CAPLUS AMERICAN CHEMICAL SOCIETY; 12 May 1984 (1984-05-12), XP002266127, retrieved from STN Database accession no. 1973:478762
J.A. CONNOR ET AL, J. CHEM. SOC. PERKIN TRANS. 1, no. 4, 1990, pages 1127 - 1132, XP001021533
R.N. PRASAD ET AL, CAN. J. CHEM., vol. 44, no. 11, 1966, pages 1247 - 1258, XP001027730
DATABASE CAPLUS AMERICAN CHEMICAL SOCIETY; 22 April 2001 (2001-04-22), XP002266129, retrieved from STN Database accession no. 1957:98876
E. MOUNETOU ET AL, J. LABELLED COMP. RADIOPHARM., vol. 41, no. 3, 1998, pages 181 - 189, XP002266165
DATABASE CAPLUS AMERICAN CHEMICAL SOCIETY; 12 May 1984 (1984-05-12), XP002266128, retrieved from STN Database accession no. 1980:471730
R. SPECKLIN ET AL, BULL. SOC. CHIM. FR., 1951, pages 621 - 626, XP000616273
"Chemical Abstracts Service Registry Handbook, 2000 Supplement; ISSN: 0093-058X; CAS Registry Number 271534-00-0 through 276887-31-1", 2001, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO,US, XP002266300
Download PDF: