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Title:
ASSAY OFISOMERISED AND/OR OPTICALLY INVERTED PROTEINS AND PROTEIN FRAGMENTS
Document Type and Number:
WIPO Patent Application WO2002095415
Kind Code:
A3
Abstract:
In an in vitro diagnostic test for osteoarthritis or rheumatoid arthritis, the amount or presence in a sample of anisomerised or optically inverted protein fragment is measured which derives from perlecan, bigylcan, decorin, fibrillin-1 or protocadherin or which is a specific sequence from aggrecan, type II collagen, COMP or CILP.

Inventors:
CHRISTGAU STEPHAN (DK)
HENRIKSEN DENNIS BANG (DK)
CLOOS PAUL ANDREAS COMPARE (DK)
Application Number:
PCT/EP2002/005612
Publication Date:
March 04, 2004
Filing Date:
May 22, 2002
Export Citation:
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Assignee:
OSTEOMETER BIO TECH AS (DK)
CHRISTGAU STEPHAN (DK)
HENRIKSEN DENNIS BANG (DK)
CLOOS PAUL ANDREAS COMPARE (DK)
International Classes:
G01N33/68; (IPC1-7): G01N33/68; C07K14/78
Domestic Patent References:
WO2001005422A22001-01-25
WO1998039653A11998-09-11
Foreign References:
US6107047A2000-08-22
Other References:
ARIKAWA-HIRASAWA E ET AL: "PERLECAN IS ESSENTIAL FOR CARTILAGE AND CEPHALIC DEVELOPMENT", NATURE GENETICS, NATURE AMERICA, NEW YORK, US, vol. 23, no. 3, November 1999 (1999-11-01), pages 354 - 358, XP001034683, ISSN: 1061-4036
COSTELL M ET AL: "PERLECAN MAINTAINS THE INTEGRITY OF CARTILAGE AND SOME BASEMENT MEMBRANES", THE JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIVERSITY PRESS, US, vol. 147, no. 5, 29 November 1999 (1999-11-29), pages 1109 - 1122, XP002906976, ISSN: 0021-9525
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