Title:
BENZO ADf BDQUINOLINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING THEM
Document Type and Number:
WIPO Patent Application WO/1986/004896
Kind Code:
A1
Abstract:
Benzo ADf BDquinoline derivatives represented by general formula (I), (wherein R1 and R2 may be the same or different, and each represents hydrogen or 1-4C alkyl, R3 and R4 may be the same or different, and each represents hydrogen, halogen, nitro, amino, hydroxy, 1-4C alkyl, 1-4C alkoxy, or 2-5C alkanoyloxy, and R5 represents hydroxyimino, amino, 1-4C alkylamino, alicyclic alkylamino, aralkylamino, acylamino, 1-4C alkoxycarbonylamino, 1-4C alkanesulfonylamino, 3-(1-4C alkyl) ureido, 3-(1-4C alkyl)thioureido or 1-4C alkylaminosulfonylamino and pharmaceutically acceptable acid addition salts thereof, process for their preparation, and medicinal compositions containing them. These compounds have analgesic, anti-inflammatory, and antipyretic effects, and are useful as non-steroidal basic analgesic and anti-inflammatory agents with no narcotic effect.
Inventors:
NAKAO TORU (JP)
SAITO TADAMASA (JP)
TERASAWA MICHIO (JP)
TAHARA TETSUYA (JP)
SAITO TADAMASA (JP)
TERASAWA MICHIO (JP)
TAHARA TETSUYA (JP)
Application Number:
PCT/JP1986/000055
Publication Date:
August 28, 1986
Filing Date:
February 10, 1986
Export Citation:
Assignee:
YOSHITOMI PHARMACEUTICAL (JP)
International Classes:
A61K31/47; A61K31/473; A61P25/04; A61P29/00; C07D221/10; (IPC1-7): C07D221/10; A61K31/47
Foreign References:
| JPS5782371A | 1982-05-22 |
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