Title:
BIMODAL DRY POWDER FORMULATION FOR INHALATION
Document Type and Number:
WIPO Patent Application WO2002062317
Kind Code:
A3
Abstract:
There is described a bimodal pharmaceutical composition comprising effective amounts of a first active ingredient which substantially comprises a coarse fraction and a second active ingredient which substantially comprise a fine fraction characterised in that the coarse fraction possesses a greater mass median aerodynamic diameter (MMDA) than the fine fraction. There is also described a method of a method of delivering a therapeutically effective amount of a substantially fine active ingredient to the lung of a patient by the co-administration with a substantially coarse active ingredient.
Inventors:
SANDERS MARK (GB)
Application Number:
PCT/GB2002/000480
Publication Date:
November 21, 2002
Filing Date:
February 05, 2002
Export Citation:
Assignee:
INNOVATA BIOMED LTD (GB)
SANDERS MARK (GB)
SANDERS MARK (GB)
International Classes:
A61K9/14; A61K9/10; A61K9/12; A61K9/72; A61K31/167; A61K31/4468; A61K31/485; A61K31/565; A61K31/57; A61K38/04; A61K38/21; A61K38/22; A61K38/27; A61K38/28; A61M15/00; A61P11/00; (IPC1-7): A61K9/14; A61K9/72; A61K31/565; A61K31/167
Domestic Patent References:
| WO1998031352A1 | 1998-07-23 | |||
| WO1995000128A1 | 1995-01-05 |
Foreign References:
| FR2584604A1 | 1987-01-16 |
Other References:
GERRITY T R: "PATHOPHYSIOLOGICAL AND DISEASE CONSTRAINTS ON AEROSOL DELIVERY", RESPIRATORY DRUG DELIVERY, XX, XX, 1990, pages 1 - 38, XP008006563
Download PDF: