BIODEGRADABLE IRON OXIDE NANOPARTICLE GEL

Title:

BIODEGRADABLE IRON OXIDE NANOPARTICLE GEL

Document Type and Number:

WIPO Patent Application WO/2014/121224

Kind Code:

A3

Abstract:

A biodegradable iron oxide nanoparticle gel for hyperthermia treatment of cancer includes a polysaccharide-based carrier matrix and starch-coated iron oxide nanoparticles. The gel has sufficient deformability to integrate into a diffuse tumor site, adheres to tissue and has sufficient mechanical properties to remain in place during hyperthermia treatment. The gel releases iron oxide nanoparticles for uptake by cancerous cells at the tumor margin.

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Inventors:

CUNKELMAN BENJAMIN P (US)
TATE JENNIFER A (US)
PETRYK ALICIA A (US)
HOOPES P JACK (US)
COLLIER ROBERT J (US)
THAPPA SARA G (US)

Application Number:

PCT/US2014/014493

Publication Date:

October 16, 2014

Filing Date:

February 03, 2014

Export Citation:

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Assignee:

DARTMOUTH COLLEGE (US)

International Classes:

A61K33/26

Foreign References:

US20120121517A1	2012-05-17
US5985312A	1999-11-16
US20110110868A1	2011-05-12
US20090062233A1	2009-03-05

Attorney, Agent or Firm:

PERRIN, Heather, F. et al. (4845 Pearl East CircleSuite 20, Boulder CO, US)

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