Title:
BIOMARKERS FOR LUNG CANCER STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2018/127055
Kind Code:
A1
Abstract:
Provided herein are methods and kits for analyzing a sample such as a biological sample obtained from a subject having, suspected of having, or being at risk for a cancer to assess presence of cancer stem cells in the sample, which is indicative of poor cancer prognosis.
Inventors:
YANG PAN-CHYR (TW)
CHEN HUEI-WEN (TW)
CHEN WAN-JIUN (TW)
CHEN HUEI-WEN (TW)
CHEN WAN-JIUN (TW)
Application Number:
PCT/CN2018/070383
Publication Date:
July 12, 2018
Filing Date:
January 03, 2018
Export Citation:
Assignee:
YANG PAN CHYR (CN)
CHEN HUEI WEN (CN)
CHEN WAN JIUN (CN)
CHEN HUEI WEN (CN)
CHEN WAN JIUN (CN)
International Classes:
G01N33/574; G01N33/577
Domestic Patent References:
| WO2013126993A1 | 2013-09-06 | |||
| WO2002012447A2 | 2002-02-14 |
Foreign References:
| CN105102614A | 2015-11-25 | |||
| CN106053821A | 2016-10-26 | |||
| AU2013203260A1 | 2013-09-12 | |||
| US6984522B2 | 2006-01-10 | |||
| US9340774B2 | 2016-05-17 |
Other References:
LEUNG, E. L. ET AL.: "Non-Small Cell Lung Cancer Cells Expressing CD 44 Are Enriched for Stem Cell -Like Properties", PLOS ONE, vol. 5, no. 11, 19 November 2010 (2010-11-19), pages 1 - 13, XP055093684
LOBBA, A. R. M. ET AL.: "Differential Expression of CD90 and CD14 Stem Cell Markers in Malignant Breast Cancer Cell Lines", CYTOMETRY PART A, vol. 81 A, no. 12, 22 October 2012 (2012-10-22), pages 1084 - 1091, XP055513263
HUANG ET AL., CANC IMMUNOL IMMU, vol. 62, 2013, pages 1439 - 1451
MAEDA ET AL., J. THER. ONCOL., vol. 9, no. 2, 2014, pages 179 - 188
FENG ET AL., AM. J. RESP. CRIT CARE MED, vol. 186, no. 10, 2012, pages 1025 - 1036
LEUNG ET AL., PLOS ONE, vol. 5, no. 11, 2010, pages e14062
MCDONAGH ET AL., CANC. LETT., vol. 372, no. 2, 2016, pages 147 - 156
"GenBank", Database accession no. NP001167575.0
DE WILDT ET AL., EUR J IMMUNOL., vol. 26, no. 3, 1996, pages 629 - 39
CHEN ET AL., N. ENGL. J. MED., vol. 356, no. 1, 2007, pages 11 - 20
LOBBA, A. R. M. ET AL.: "Differential Expression of CD90 and CD14 Stem Cell Markers in Malignant Breast Cancer Cell Lines", CYTOMETRY PART A, vol. 81 A, no. 12, 22 October 2012 (2012-10-22), pages 1084 - 1091, XP055513263
HUANG ET AL., CANC IMMUNOL IMMU, vol. 62, 2013, pages 1439 - 1451
MAEDA ET AL., J. THER. ONCOL., vol. 9, no. 2, 2014, pages 179 - 188
FENG ET AL., AM. J. RESP. CRIT CARE MED, vol. 186, no. 10, 2012, pages 1025 - 1036
LEUNG ET AL., PLOS ONE, vol. 5, no. 11, 2010, pages e14062
MCDONAGH ET AL., CANC. LETT., vol. 372, no. 2, 2016, pages 147 - 156
"GenBank", Database accession no. NP001167575.0
DE WILDT ET AL., EUR J IMMUNOL., vol. 26, no. 3, 1996, pages 629 - 39
CHEN ET AL., N. ENGL. J. MED., vol. 356, no. 1, 2007, pages 11 - 20
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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