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Title:
CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2001/007400
Kind Code:
A1
Abstract:
Substances inhibiting cell adhesion mediated by adhesion molecules (in particular, VLA-4) which enable the prevention and treatment of inflammatory diseases caused by leukocyte (for example, monocyte, lymphocyte or eosinocyte) infiltration. A group of carboxylic acid derivatives exemplified by a compound represented by the formula (140) and adhesion molecule inhibitors containing the same as the active ingredient

Inventors:
TAKAHASHI TOSHIYA (JP)
TAKANO YOSHIO (JP)
ISHIGAKI TAKESHI (JP)
FUNAHASHI MIYUKI (JP)
KANEKO MASAYUKI (JP)
KAINOH MIE (JP)
Application Number:
PCT/JP2000/004965
Publication Date:
February 01, 2001
Filing Date:
July 26, 2000
Export Citation:
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Assignee:
TORAY INDUSTRIES (JP)
TAKAHASHI TOSHIYA (JP)
TAKANO YOSHIO (JP)
ISHIGAKI TAKESHI (JP)
FUNAHASHI MIYUKI (JP)
KANEKO MASAYUKI (JP)
KAINOH MIE (JP)
International Classes:
A61P29/00; A61P43/00; C07C229/22; C07C229/36; C07C233/22; C07C233/47; C07C233/51; C07C233/83; C07C233/87; C07C235/12; C07C235/34; C07C235/52; C07C235/60; C07C237/12; C07C237/22; C07C251/24; C07C271/22; C07C275/28; C07C275/30; C07C275/42; C07C311/21; C07C323/59; C07D207/08; C07D239/46; C07K5/02; C07K5/06; C07K5/078; C07K5/097; A61K38/00; (IPC1-7): C07C233/51; A61K31/198; A61K31/216; A61K31/22; A61K31/222; A61K31/235; A61K31/27; A61K31/277; A61K31/40; A61K31/505; A61K38/00; A61P29/00; A61P43/00; C07C233/87; C07C235/12; C07C235/66; C07C237/22; C07C275/42; C07C311/21; C07C323/59; C07C329/06; C07D207/08; C07D239/47; C07K5/062
Domestic Patent References:
WO1996022966A11996-08-01
Attorney, Agent or Firm:
Tanigawa, Hidejiro (Patent Firm 6F Iwata Bldg. 5-1, Iidabashi 4-chome Chiyoda-ku Tokyo, JP)
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