Title:
CASPASE INHIBITORS AS THERAPEUTICS FOR NEURAL AND ORGAN INJURY AND IMAGING
Document Type and Number:
WIPO Patent Application WO/2012/021800
Kind Code:
A3
Abstract:
Compounds, pharmaceutically acceptable salts thereof, and compositions useful as caspase inhibitors are disclosed. Certain compounds are also useful for the treatment of neural or organ injury. Other compounds are useful as neural and organ-specific imaging agents.
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Inventors:
WANG KEVIN KA-WANG (US)
ZHANG ZHIQUN (US)
CHENG XUE-MIN (US)
CAPRATHE BRADLEY (US)
ZHANG ZHIQUN (US)
CHENG XUE-MIN (US)
CAPRATHE BRADLEY (US)
Application Number:
PCT/US2011/047579
Publication Date:
May 24, 2012
Filing Date:
August 12, 2011
Export Citation:
Assignee:
BANYAN BIOMARKERS (US)
WANG KEVIN KA-WANG (US)
ZHANG ZHIQUN (US)
CHENG XUE-MIN (US)
CAPRATHE BRADLEY (US)
WANG KEVIN KA-WANG (US)
ZHANG ZHIQUN (US)
CHENG XUE-MIN (US)
CAPRATHE BRADLEY (US)
International Classes:
C07C237/22; A61K31/165; A61K49/10; A61P25/00; C07C233/53
Domestic Patent References:
| WO2007007162A1 | 2007-01-18 |
Foreign References:
| US20020042376A1 | 2002-04-11 |
Other References:
LINTON, STEVEN D. ET AL.: "Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke.", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS., vol. 14, 2004, pages 2685 - 2691, XP002510183, DOI: doi:10.1016/J.BMCL.2003.12.106
Attorney, Agent or Firm:
MARSHALL, Ryan, L. et al. (P.O. Box 10087Chicago, IL, US)
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