Title:
CATALYST FOR SILYLATION REACTION OF AROMATIC AMINE
Document Type and Number:
WIPO Patent Application WO/2020/088119
Kind Code:
A1
Abstract:
Disclosed is the use of Al(C6F5)3 as a catalyst for silylation reaction of an aromatic amine, which provides a novel reaction catalyst for the synthesis of a silylated aromatic amine. Aluminium element is rich in content and low in cost. Al(C6F5)3 can be used as a catalyst to effectively reduce the synthesis cost of a silylated aromatic amine. At the same time, due to the low toxicity of aluminium element, the environmental friendliness of the synthesis process is improved. The Al(C6F5)3 has a high catalytic activity, and the yield of the silylated aromatic amine prepared is high. In addition, using Al(C 6F 5) 3 as a catalyst does not require the use of a hydrogen acceptor, and a silylation reaction only occurs at a C-H bond in the para position of the aromatic amine, which simplifies the post-treatment process of a product; and the reaction has a high selectivity.
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Inventors:
YUE ZHEN (CN)
ZHAO JIYANG (CN)
ZHAO JIYANG (CN)
Application Number:
PCT/CN2019/105678
Publication Date:
May 07, 2020
Filing Date:
September 12, 2019
Export Citation:
Assignee:
UNIV NANJING XIAOZHUANG (CN)
International Classes:
B01J31/14; C07F7/08
Foreign References:
| CN109529930A | 2019-03-29 | |||
| CN101010326A | 2007-08-01 |
Other References:
HAN, YUXI: "Lewis Acid-Catalyzed C-H Silylation of Indoles and Synthesis of Silicon-Polymer Materials", CHINESE DOCTORAL DISSERTATIONS FULL-TEXT DATABASE, 1 May 2018 (2018-05-01), pages 1 - 202, XP055699607
HAN, YUXI ET AL.: "Switchable C−H Silylation of Indoles Catalyzed by a Thermally Induced Frustrated Lewis Pair", ACS CATALYSIS, vol. 8, no. 9, 8 August 2018 (2018-08-08), pages 8765 - 8773, XP055698490, ISSN: 2155-5435, DOI: 10.1021/acscatal.8b01847
HAN, YUXI ET AL.: "Switchable C−H Silylation of Indoles Catalyzed by a Thermally Induced Frustrated Lewis Pair", ACS CATALYSIS, vol. 8, no. 9, 8 August 2018 (2018-08-08), pages 8765 - 8773, XP055698490, ISSN: 2155-5435, DOI: 10.1021/acscatal.8b01847
Attorney, Agent or Firm:
SUNSHINE INTELLECTUAL PROPERTY INTERNATIONAL CO., LTD. (CN)
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