Title:
CATECHINS FOR THE TREATMENT OF FIBRILLOGENESIS IN ALZHEIMER'S DISEASE, PARKINSON'S DISEASE, SYSTEMIC AA AMYLOIDOSIS, AND OTHER AMYLOID DISORDERS
Document Type and Number:
WIPO Patent Application WO/2003/013442
Kind Code:
A2
Abstract:
A method of treating an amyloid disease, or a disease characterized by alpha-synuclein or NAC fibrillogenesis, in a mammalian subject. The method includes administering to the mammal a therapeutically effective amount of a various disclosed catechins or green tea extract. A pharmaceutical composition comprising a therapeutically effective amount of a catechin and pharmaceutically acceptable excipient. The therapeutic amount of the catechin or green tea extracts is selected for efficacy in treating amyloid, alpha-synuclein or NAC fibrillogenesis in a mammalian subject.
Inventors:
CASTILLO GERARDO M
CHOI PAULA Y
CUMMINGS JOEL A
NGUYEN BETH P
SNOW ALAN D
CHOI PAULA Y
CUMMINGS JOEL A
NGUYEN BETH P
SNOW ALAN D
Application Number:
PCT/US2002/007755
Publication Date:
February 20, 2003
Filing Date:
March 15, 2002
Export Citation:
Assignee:
PROTEOTECH INC (US)
International Classes:
A61K31/215; C07D311/62; A61K31/353; A61P7/12; A61P25/00; A61P25/16; A61P25/28; (IPC1-7): A61K/
Domestic Patent References:
| WO1998051302A1 | 1998-11-19 |
Other References:
See also references of EP 1372682A2
Attorney, Agent or Firm:
Dwyer, Patrick M. (Inc 1818 Westlake Avenue N. Suite 11, Seattle WA, US)
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