Title:
COMPOSITION CONTAINING AMLODIPINE, OR A SALT OR FELODIPINE AND ANACE INHIBITOR
Document Type and Number:
WIPO Patent Application WO1996028185
Kind Code:
A3
Abstract:
Methods of treating congestive heart failure in a mammal, especially a human, by co-administration of (1) amlodipine, a pharmaceutically acceptable salt of amlodipine; (2) an ACE inhibitor; and optionally (3) a diuretic and/or (4) digoxin.
Inventors:
CROPP ANNE B (US)
KRASKA ALLEN R (US)
KRASKA ALLEN R (US)
Application Number:
PCT/IB1996/000145
Publication Date:
October 17, 1996
Filing Date:
February 26, 1996
Export Citation:
Assignee:
PFIZER (US)
CROPP ANNE B (US)
KRASKA ALLEN R (US)
CROPP ANNE B (US)
KRASKA ALLEN R (US)
International Classes:
A61K31/40; A61K31/4422; A61K31/401; A61K31/44; A61K31/54; A61K31/549; A61K31/704; A61K38/55; A61K45/00; A61P9/00; A61P9/04; (IPC1-7): A61K38/55
Foreign References:
| EP0265685A2 | 1988-05-04 |
Other References:
SUN, J.X. ET AL: "Pharmacokinetic interaction study between benazepril and amlodipine in healthy subjects", EUR. J. CLIN. PHARMACOL., 1994, 285-9, XP000578582
ELKAYAM U. ET AL: "Calcium channel blockers in heart failure", J. AM. COLL. CARDIOL., 1993, 22/4 SUPPL. A (139A-144A), USA, XP000578690
PACKER M ET AL: "RANDOMIZED MULTICENTER DOUBLE-BLIND PLACEBO-CONTROLLED EVALUATION OF AMLODIPINE IN PATIENTS WITH MILD-TO-MODERATE HEART FAILURE", AMERICAN COLLEGE OF CARDIOLOGY 40TH ANNUAL SCIENTIFIC SESSION, ATLANTA, GEORGIA, USA, MARCH 3-7, 1991. J AM COLL CARDIOL, 17 (2 SUPPL. A). 1991. 274A., XP000578571
COHN J.N.: "Vasodilators in heart failure. Conclusions from V-HeFT II and rationale for Y-HeFT III", DRUGS, 1994, 47/SUPPL. 4 (47-58), NEW ZEALAND, XP000578695
ELKAYAM U. ET AL: "Calcium channel blockers in heart failure", J. AM. COLL. CARDIOL., 1993, 22/4 SUPPL. A (139A-144A), USA, XP000578690
PACKER M ET AL: "RANDOMIZED MULTICENTER DOUBLE-BLIND PLACEBO-CONTROLLED EVALUATION OF AMLODIPINE IN PATIENTS WITH MILD-TO-MODERATE HEART FAILURE", AMERICAN COLLEGE OF CARDIOLOGY 40TH ANNUAL SCIENTIFIC SESSION, ATLANTA, GEORGIA, USA, MARCH 3-7, 1991. J AM COLL CARDIOL, 17 (2 SUPPL. A). 1991. 274A., XP000578571
COHN J.N.: "Vasodilators in heart failure. Conclusions from V-HeFT II and rationale for Y-HeFT III", DRUGS, 1994, 47/SUPPL. 4 (47-58), NEW ZEALAND, XP000578695
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