COMPOSITION CONTAINING BIOLOGICALLY ACTIVE SUBSTANCE

Title:

COMPOSITION CONTAINING BIOLOGICALLY ACTIVE SUBSTANCE

Document Type and Number:

WIPO Patent Application WO/2014/006867

Kind Code:

A1

Abstract:

The purpose of the present invention is to provide a composition containing a biologically active substance, which has good moldability to such an extent that a satisfactory granular preparation can be prepared therefrom without the need of cutting using a water-cooled cutter, and which can fulfill the performance required for a lumen-bypassing preparation or the like. The composition containing a biologically active substance according to the present invention comprises: 10 to 50 mass% of a protecting substance which comprises (1a) a linear or branched saturated or unsaturated aliphatic monocarboxylic acid having a melting point of lower than 50˚C and having 8 to 24 carbon atoms, (1b) a linear or branched saturated or unsaturated aliphatic monocarboxylic acid having a melting point of 50˚C or higher and having 8 to 24 carbon atoms and (2) a calcium salt of a linear or branched saturated or unsaturated aliphatic monocarboxylic acid, which has a calcium content of 8 to 12 mass% and having 12 to 24 carbon atoms; and 50 to 90 mass% of the biologically active substance which is dispersed in the protecting substance.

Inventors:

MORISHIMA KO (JP)
ABE SHUICHI (JP)
TAKESHI YUTAKA (JP)

Application Number:

PCT/JP2013/004062

Publication Date:

January 09, 2014

Filing Date:

July 01, 2013

Export Citation:

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Assignee:

NIPPON SODA CO (JP)
NISSO FINE CO LTD (JP)

International Classes:

A23K1/16; A23K1/18; A61K9/42; A61K31/198; A61K45/00; A61K47/12; A61K47/42; A61P1/00

Domestic Patent References:

WO1998024329A1

1998-06-11

Foreign References:

JPH09187228A	1997-07-22
JP2003261671A	2003-09-19
JPH10113923A	1998-05-06
JPH06114365A	1994-04-26
JPH10215789A	1998-08-18

Other References: