Title:
COMPOSITION FOR CONTROLLING CHROMATIN STRUCTURE
Document Type and Number:
WIPO Patent Application WO/2013/162054
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a composition for controlling a chromatin structure. A composition of the present invention contains: (1) a polymer which is selected from the group consisting of amphoteric polymers, anionic polymers and nonionic polymers having a specific main chain skeleton; or (2) a carrier which encloses two or more kinds of substances selected from the group consisting of expression vectors containing a gene such as a gene encoding histone acetyltransferase and inhibitors such as histone acetylation inhibitors.
More Like This:
Inventors:
KAWAKAMI HIROYOSHI (JP)
ASAYAMA SHOICHIRO (JP)
HAZAMA KENICHI (JP)
ASABA YUTARO (JP)
NOGUCHI DAISUKE (JP)
ASAYAMA SHOICHIRO (JP)
HAZAMA KENICHI (JP)
ASABA YUTARO (JP)
NOGUCHI DAISUKE (JP)
Application Number:
PCT/JP2013/062737
Publication Date:
October 31, 2013
Filing Date:
April 24, 2013
Export Citation:
Assignee:
UNIV TOKYO METROPOLITAN (JP)
International Classes:
C12N15/09; A61K31/713; A61K47/30; A61K48/00; A61P35/00; A61P43/00
Domestic Patent References:
| WO2011068522A1 | 2011-06-09 | |||
| WO2008029565A1 | 2008-03-13 |
Other References:
YUTARO ASABA ET AL.: "Atarashii Idenshi Sosa o Mezashita Epigenetics Kogaku", POLYMER PREPRINTS, JAPAN, vol. 60, no. 2, 2011, pages 4781 - 4782
KAZANTSEV, A. G. ET AL.: "Therapeutic application of histone deacetylase inhibitors for central nervous system disorders.", NAT. REV., vol. 7, 2008, pages 854 - 868
KAZANTSEV, A. G. ET AL.: "Therapeutic application of histone deacetylase inhibitors for central nervous system disorders.", NAT. REV., vol. 7, 2008, pages 854 - 868
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)
Ono Shinjiro (JP)
Download PDF: