Title:
COMPOSITION FOR DIAGNOSING OR TREATING CONDITIONS ASSOCIATED WITH INCREASED ELF4E ACTIVITY COMPRISING ELF4E INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2021/045538
Kind Code:
A1
Abstract:
The present invention relates to a composition, kit or method for diagnosing or treating conditions associated with increased eIF4E activity, the composition comprising an eIF4E inhibitor.
Inventors:
LEE JEONG HO (KR)
KIM JANG KEUN (KR)
KIM BYUNG TAE (KR)
KIM SUN-GYUN (KR)
KIM JANG KEUN (KR)
KIM BYUNG TAE (KR)
KIM SUN-GYUN (KR)
Application Number:
PCT/KR2020/011877
Publication Date:
March 11, 2021
Filing Date:
September 03, 2020
Export Citation:
Assignee:
SOVARGEN CO LTD (KR)
International Classes:
A61K48/00; A61K31/155; A61K31/7088; A61P25/00; C12Q1/6883; G01N33/68
Domestic Patent References:
| WO2001096388A2 | 2001-12-20 | |||
| WO2001096389A2 | 2001-12-20 |
Foreign References:
| KR100750788B1 | 2007-08-20 | |||
| KR20140064982A | 2014-05-28 | |||
| US20090203765A1 | 2009-08-13 | |||
| US9096851B2 | 2015-08-04 | |||
| US8410074B2 | 2013-04-02 | |||
| US8252762B2 | 2012-08-28 | |||
| US7601700B2 | 2009-10-13 | |||
| US9629346B2 | 2017-04-25 |
Other References:
MÜHLEBNER A., BONGAARTS A., SARNAT H. B., SCHOLL T., ARONICA E.: "dysregulations: challenges and perspectives", JOURNAL OF ANATOMY., CAMBRIDGE UNIVERSITY PRESS, CAMBRIDGE,, GB, vol. 235, no. 3, 1 September 2019 (2019-09-01), GB, pages 521 - 542, XP055787680, ISSN: 0021-8782, DOI: 10.1111/joa.12956
ASTRINIDIS ARISTOTELIS, HENSKE ELIZABETH P: "Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease", ONCOGENE, NATURE PUBLISHING GROUP UK, LONDON, vol. 24, no. 50, 1 November 2005 (2005-11-01), London, pages 7475 - 7481, XP055787681, ISSN: 0950-9232, DOI: 10.1038/sj.onc.1209090
ONCOGENE, vol. 23, no. 18, 19 April 2004 (2004-04-19), pages 3189 - 99
J. CLIN. INVEST., vol. 117, 2007, pages 2638 - 2648
EPILEPSIA, vol. 52, 2011, pages 158 - 174
"NCBI", Database accession no. NP_001138360.1
BAILEY TLELKAN C.: "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", PROC. SECOND INT. CONF. INTELL. SYST. MOL. BIOL, 1994, pages 28 - 36
LEE JH ET AL., DE NOVO SOMATIC MUTATIONS IN COMPONENTS OF THE PI3K-AKT3-MTOR PATHWAY CAUSE HEMIMEGALENCEPHALY NAT. GENET, vol. 44, no. 8, 2012, pages 941 - 945
See also references of EP 4026567A4
ASTRINIDIS ARISTOTELIS, HENSKE ELIZABETH P: "Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease", ONCOGENE, NATURE PUBLISHING GROUP UK, LONDON, vol. 24, no. 50, 1 November 2005 (2005-11-01), London, pages 7475 - 7481, XP055787681, ISSN: 0950-9232, DOI: 10.1038/sj.onc.1209090
ONCOGENE, vol. 23, no. 18, 19 April 2004 (2004-04-19), pages 3189 - 99
J. CLIN. INVEST., vol. 117, 2007, pages 2638 - 2648
EPILEPSIA, vol. 52, 2011, pages 158 - 174
"NCBI", Database accession no. NP_001138360.1
BAILEY TLELKAN C.: "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", PROC. SECOND INT. CONF. INTELL. SYST. MOL. BIOL, 1994, pages 28 - 36
LEE JH ET AL., DE NOVO SOMATIC MUTATIONS IN COMPONENTS OF THE PI3K-AKT3-MTOR PATHWAY CAUSE HEMIMEGALENCEPHALY NAT. GENET, vol. 44, no. 8, 2012, pages 941 - 945
See also references of EP 4026567A4
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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