Title:
COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES, COMPRISING CARDIAC STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2021/187895
Kind Code:
A1
Abstract:
The present invention relates to: a pharmaceutical composition for preventing or treating angiogenesis-dependent diseases, comprising, as an active ingredient, cardiac stem cells having increased angiogenesis or a culture medium thereof; and the like.
Inventors:
LEE SEUNG JIN (KR)
KIM HEEJUNG (KR)
SHIN JI YOUNG (KR)
JEON JEONG HWA (KR)
SEO CHAE WON (KR)
KIM HEEJUNG (KR)
SHIN JI YOUNG (KR)
JEON JEONG HWA (KR)
SEO CHAE WON (KR)
Application Number:
PCT/KR2021/003310
Publication Date:
September 23, 2021
Filing Date:
March 17, 2021
Export Citation:
Assignee:
HIERABIO INC (KR)
International Classes:
C12N5/0775; A61K35/34; A61P9/10; C12N15/63
Domestic Patent References:
| WO2011067317A1 | 2011-06-09 |
Foreign References:
| KR20180071665A | 2018-06-28 | |||
| KR20090010662A | 2009-01-30 |
Other References:
PEI XING, HEEJUNG KIM, MINJOO LEE, NANA WANG, JIYOUNG SHIN, SEUNGJIN LEE, MIYUN YOON, VICTOR C YANG, HUINING HE: "Local delivery of cardiac stem cells overexpressing HIF-1α promotes angiogenesis and muscular tissue repair in a hind limb ischemia model", JOURNAL OF CONTROLLED RELEASE, vol. 322, 16 March 2020 (2020-03-16), pages 610 - 621, XP055851037, DOI: 10.1016/j.jconrel.2020.03.017
DATABASE PROTEIN 22 July 2014 (2014-07-22), ANONYMOUS: "PREDICTED: hypoxia-inducible factor 1-alpha [Galeopterus variegatus]", XP055851042, retrieved from NCBI Database accession no. XP_008564341
HIRANMOY DAS, JON C. GEORGE, MATTHEW JOSEPH, MANJUSRI DAS, NASREEN ABDULHAMEED, ANNA BLITZ, MAHMOOD KHAN, RAMASAMY SAKTHIVEL, HAI-: "Stem Cell Therapy with Overexpressed VEGF and PDGF Genes Improves Cardiac Function in a Rat Infarct Model", PLOS ONE, vol. 4, no. 10, pages e7325, XP055092609, DOI: 10.1371/journal.pone.0007325
DATABASE PROTEIN 22 July 2014 (2014-07-22), ANONYMOUS: "PREDICTED: hypoxia-inducible factor 1-alpha [Galeopterus variegatus]", XP055851042, retrieved from NCBI Database accession no. XP_008564341
HIRANMOY DAS, JON C. GEORGE, MATTHEW JOSEPH, MANJUSRI DAS, NASREEN ABDULHAMEED, ANNA BLITZ, MAHMOOD KHAN, RAMASAMY SAKTHIVEL, HAI-: "Stem Cell Therapy with Overexpressed VEGF and PDGF Genes Improves Cardiac Function in a Rat Infarct Model", PLOS ONE, vol. 4, no. 10, pages e7325, XP055092609, DOI: 10.1371/journal.pone.0007325
Attorney, Agent or Firm:
LEE, Myoung-Jin (KR)
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