Title:
COMPOUND BEARING TWO 2,6-DIIODOPHENOL-4-YL GROUPS AND DIAGNOSTIC DRUG FOR IODINE ALLERGY
Document Type and Number:
WIPO Patent Application WO/1995/032173
Kind Code:
A1
Abstract:
A compound bearing at least two 2,6-diiodophenol-4-yl groups represented by formula (IV), particularly a polymer composed of two to eight iodinated tyrosine molecules condensed with each other. This compound is useful as a diagnostic drug for iodine allergy and the diagnostic method comprises administering the drug to the patient to examine the intracutaneous reaction.
Inventors:
SUGIHARA YOSHIKI (JP)
SHIONOYA HIROSHI (JP)
YAMATSU KIYOMI (JP)
SHIONOYA HIROSHI (JP)
YAMATSU KIYOMI (JP)
Application Number:
PCT/JP1995/000997
Publication Date:
November 30, 1995
Filing Date:
May 24, 1995
Export Citation:
Assignee:
EISAI CO LTD (JP)
SUGIHARA YOSHIKI (JP)
SHIONOYA HIROSHI (JP)
YAMATSU KIYOMI (JP)
SUGIHARA YOSHIKI (JP)
SHIONOYA HIROSHI (JP)
YAMATSU KIYOMI (JP)
International Classes:
A61K49/04; C07C237/20; C07K5/06; C07K5/08; C07K5/10; A61K38/00; (IPC1-7): C07C39/367; C07C237/20; C07C237/22; C07K5/065; C07K5/087; C07K5/107; C07K7/06; A61K49/00
Foreign References:
| JPH03120296A | 1991-05-22 |
Other References:
KHIM, PROM-ST. (MOSCOW), (1989), (2), LOKHONINA T.I. et al., pages 106-9.
ANAL. BIOCHEM., (1993), 210(1), TSOMIDES THEOBORE J. et al., pages 129-35.
J. LABELLED COMPD. RADIOPHARM., (1980), 17(6), MAURIZIS J.C. et al., pages 901-9.
SYNTH. APPL. ISOT. LABELED COMPD., PROC. INT. SYMP., (1983), Meeting Date 1982, HEYS J. RICHARD et al., Editors: DUNCAN WILLIAM P. et al., pages 425-6.
EXPERIENTIA, (1985), 41(3), BERNARD D. et al., pages 385-7.
ANAL. BIOCHEM., (1993), 210(1), TSOMIDES THEOBORE J. et al., pages 129-35.
J. LABELLED COMPD. RADIOPHARM., (1980), 17(6), MAURIZIS J.C. et al., pages 901-9.
SYNTH. APPL. ISOT. LABELED COMPD., PROC. INT. SYMP., (1983), Meeting Date 1982, HEYS J. RICHARD et al., Editors: DUNCAN WILLIAM P. et al., pages 425-6.
EXPERIENTIA, (1985), 41(3), BERNARD D. et al., pages 385-7.
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