Title:
COMPOUND USABLE IN CONJUGATION REACTION AND CONJUGATE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/114528
Kind Code:
A1
Abstract:
The present application provides a compound usable in a coupling reaction and a conjugate thereof. Further provided in the present application are a synthetic intermediate of the compound and the conjugate thereof, a synthesis method, and a use of the conjugate in preparing a drug for the treatment or prevention of an oncological disease.
Inventors:
TIAN QIANG (CN)
ZHANG YITAO (CN)
LONG DONG (CN)
LIAO MENCHANG (CN)
ZHOU QIN (CN)
SONG HONGMEI (CN)
GE JUNYOU (CN)
ZHANG YITAO (CN)
LONG DONG (CN)
LIAO MENCHANG (CN)
ZHOU QIN (CN)
SONG HONGMEI (CN)
GE JUNYOU (CN)
Application Number:
PCT/CN2023/134003
Publication Date:
June 06, 2024
Filing Date:
November 24, 2023
Export Citation:
Assignee:
SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
A61K45/00; C07D487/04; A61P35/00; A61P37/02; C07D271/107; C07D403/14
Domestic Patent References:
| WO2022253033A1 | 2022-12-08 |
Foreign References:
| CN113549127A | 2021-10-26 | |||
| CN109232464A | 2019-01-18 | |||
| US20220024904A1 | 2022-01-27 | |||
| US2993901A | 1961-07-25 | |||
| CN113264900A | 2021-08-17 | |||
| CN113603703A | 2021-11-05 | |||
| CN113698414A | 2021-11-26 | |||
| CN112341521A | 2021-02-09 | |||
| CN111295389A | 2020-06-16 |
Other References:
DATABASE Registry 22 June 1990 (1990-06-22), ANONYMOUS: " 2-Pyrimidinamine, 4,6-bis(methylsulfonyl)- (CA INDEX NAME)", XP093177137, retrieved from STNext Database accession no. 127726-67-4
DATABASE Registry 29 October 2004 (2004-10-29), ANONYMOUS: "Benzenemethanamine, 3,5-bis(methylsulfonyl)- (CA INDEX NAME)", XP093177140, retrieved from STNext Database accession no. 771573-23-0
DATABASE Registry 6 May 2005 (2005-05-06), ANONYMOUS: "Benzamide, 3,5-bis(methylsulfonyl)- (CA INDEX NAME)", XP093177145, retrieved from STNext Database accession no. 849924-85-2
DATABASE Registry 13 August 2008 (2008-08-13), ANONYMOUS: "Benzenepropanoic acid, 3,5-bis(methylsulfonyl)- (CA INDEX NAME)", XP093177150, retrieved from STNext Database accession no. 1040682-15-2
DATABASE Registry 2 August 2009 (2009-08-02), ANONYMOUS: "Benzenemethanamine, 3,5-bis(methylsulfonyl)-, hydrochloride (1:1) (CA INDEX NAME)", XP093177155, retrieved from STNext Database accession no. 171787-85-1
DATABASE Registry 29 October 2004 (2004-10-29), ANONYMOUS: "Benzenemethanamine, 3,5-bis(methylsulfonyl)- (CA INDEX NAME)", XP093177140, retrieved from STNext Database accession no. 771573-23-0
DATABASE Registry 6 May 2005 (2005-05-06), ANONYMOUS: "Benzamide, 3,5-bis(methylsulfonyl)- (CA INDEX NAME)", XP093177145, retrieved from STNext Database accession no. 849924-85-2
DATABASE Registry 13 August 2008 (2008-08-13), ANONYMOUS: "Benzenepropanoic acid, 3,5-bis(methylsulfonyl)- (CA INDEX NAME)", XP093177150, retrieved from STNext Database accession no. 1040682-15-2
DATABASE Registry 2 August 2009 (2009-08-02), ANONYMOUS: "Benzenemethanamine, 3,5-bis(methylsulfonyl)-, hydrochloride (1:1) (CA INDEX NAME)", XP093177155, retrieved from STNext Database accession no. 171787-85-1
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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