COMPOUNDS AS NUCLEAR TRANSPORT MODULATORS AND USES THEREOF

Title:

COMPOUNDS AS NUCLEAR TRANSPORT MODULATORS AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2019/232724

Kind Code:

A1

Abstract:

The present invention relates compounds of Formula (I) - (V), as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as nuclear transport modulators. The present invention also relates to uses of the compounds or pharmaceutical compositions in treating or preventing certain neurological disorders and diseases as well as cancer in humans.

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Inventors:

XIANG JIA-NING (CN)
QI ZUDE (CN)
LIU XIANBO (CN)
NING DEZHENG (CN)

Application Number:

PCT/CN2018/090151

Publication Date:

December 12, 2019

Filing Date:

June 06, 2018

Export Citation:

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Assignee:

XW LAB INC (GB)
XW LAB INC (GB)

International Classes:

C07D249/08; A61K31/4196; A61K31/454; A61K31/497; C07D233/00; C07D247/00; C07D249/00; C07D249/02; C07D257/04; C07D271/02; A61P25/00

Domestic Patent References:

WO2013019561A1	2013-02-07
WO2018098472A1	2018-05-31
WO2014205393A1	2014-12-24
WO2014152263A1	2014-09-25

Attorney, Agent or Firm:

TSINGYIHUA INTELLECTUAL PROPERTY LLC (CN)

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