CONTROL AGENT FOR INITIAL STAGE OF G1 PHASE OF CELL CYCLE

WIPO Patent Application WO/2021/157689

A1

The present invention addresses the problem of providing a cell cycle control agent based on a novel mechanism, by identifying a novel gene involved in a control mechanism of a cell cycle for canceration or differentiation of cells and using the gene and a translation product thereof.　The present invention provides a control agent for the initial stage of the G1 phase of the cell cycle, said control agent containing: C7orf26 gene having the activity of arresting the cell cycle at the initial stage of the G1 phase and causing a transition from the G1 phase to the G0 phase; and a translation product thereof.

WO/2006/043271	NOVEL NUCLEOTIDE AND AMINO ACID SEQUENCES, AND ASSAYS AND METHODS OF USE THEREOF FOR DIAGNOSIS
WO/2004/053075	COMPOSITIONS, SPLICE VARIANTS AND METHODS RELATING TO BREAST SPECIFIC GENES AND PROTEINS
WO/2021/251466	EFFICIENT METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS

AZUMA NORIYUKI (JP)
YOKOI TADASHI (JP)
TANAKA TAKU (JP)
MATSUZAKA EMIKO (JP)
NISHINA SACHIKO (JP)
NISHINA HIROSHI (JP)

PCT/JP2021/004293

August 12, 2021

February 05, 2021

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AZUMA NORIYUKI (JP)

C12N15/12; A61K35/76; A61K38/16; A61P35/00; C07K14/47; C12N5/071; C12N5/10; C12N15/63

JP2003088388A	2003-03-25
US20100190656A1	2010-07-29
JP2014513138A	2014-05-29

DATABASE UniProtKB [online] 1 December 2001 (2001-12-01), "RecName: Full=Uncharacterized protein C7orf26", XP055845880, retrieved from UniProt Database accession no. Q96N11
PARK, SUNG-HOON ET AL.: "Investigating the genetic variations of antiphospholipid syndrome by high-throughput exome sequencing", 2016 ACR/ARHP ANNUAL MEETING, 2016, pages 1 - 2, XP055845870

HIRAKI & ASSOCIATES (JP)

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