TECHNICAL FIELD

The present invention relates to a composition which can be used in cosmetic and personal care areas like regenerative cream, care cream, massage oil, humidifier, soap, skin cleaner, lotion, sun cream, ointment, burn cream and which has an effect providing increase of cell viability.

PRIOR ART

Humans were meeting their various needs by using herbs in ancient times. However, in time, the production of artificial active substances by means of synthesizing method has increased since the needs of increasing human population cannot be met any more. As the effects of the synthesized products on humans and nature increase in time, humans have a trend to natural products. As a result of this, natural cosmetic market has begun to widen.

Herbal cosmetic products are personal care products which provide health and beauty by bringing together raw substances where each stage is controlled and by accepting human health and ecologic balance as the basic principle without being subjected to any chemical process. In order for a cosmetic product to be approved as “herbal”, all stages including growing up, collecting and turning into cosmetic product for the plants must be audited by international certification companies.

As known in the art, in herbal care topical and pharmaceutical products, almond oil, jojoba oil, coconut oil, avocado oil, argan oil, aspir oil, shea oil, sesame oil, lavender oil, camellia oil, rose oil, viola oil, tea seed oil, wheat germ oil, castor oil, inca nut oil, garlic oil, cotton oil, corn oil, orchid oil, olive oil and various other herbal, vegetable and fruit oils are used.

When cosmetic and personal care materials are used, they have components which provide solving of problems like acne, fungus, ageing, inflammation, diaper rash, etc. Oil acids like linolenic acid, oleic acid and palmitic acid are accepted as valuable oil acids for cosmetic and personal care products. In the article formed by M. Sezgin and the study group and having title “Determination of efficiency and quality values of some cephalaria (Cephalaria Syriaca L.) genotypes in different ecologic conditions in Turkey”, it is mentioned that the oil amount in cephalaria seeds is between 21% and 26%. Within this context, the usage of cephalaria as oil herb is known in the present art. Moreover, again in this article, it is also mentioned that cephalaria oil is suitable for use in soap production thanks to the “myristic acid” which exists in cephalaria oil with suitable proportion.

In the master’s thesis with title “Searching the antioxidant, antimicrobial, antifungal, anti biofilm characteristics and seed morphology of cephalaria plant (Cephalaria Syriaca L) grown in Turkey”, the antibacterial, antifungal, anti-biofilm and antioxidant activities of the different concentrations of cephalaria oil dissolved in dimethyl sulphoxide have been searched.

The present invention relates to obtaining a composition which provides increase of the cell viability thanks to components provided in the body thereof and which can be used in cosmetic and personal care areas like regenerative cream, care cream, massage oil, humidifier, soap, skin cleaner, lotion, sun cream, ointment, burn cream and which have high oil acid ingredient.

BRIEF DESCRIPTION OF THE INVENTION

The present invention relates to a cosmetic and topical composition, for bringing new additional advantages to the related technical field.

An object of the present invention is to provide a cosmetic and topical composition in cosmetic and personal care areas in forms of cream, care-massage oil, gel, lotion, cleaning product, etc.

An object of the present invention is to provide a cosmetic and topical composition which provides elimination of the problems like acne, fungus, ageing, inflammation, diaper rash, etc.

An object of the present invention is to provide a cosmetic and topical composition which increases cell viability and which has repairing characteristics.

An object of the present invention is to provide a cosmetic and topical composition which shows antiseptic-analgesic effect and which functions as ache eliminator and as infection preventer. In order to realize the abovementioned objects and the objects which are to be deducted from the detailed description below, the present invention relates to a cosmetic and topical composition. Accordingly, said composition comprises at least one diluting component and cephalaria oil which increases cell viability and which comprises high oil acid with specific weight proportions. By means of this, a cosmetic and topical composition is obtained which has high oil acid value as desired.

In a possible embodiment of the present invention, the cosmetic and topical composition comprises cephalaria oil at a value between 0.7% and 75% by weight.

In a possible embodiment of the present invention, in the body of the cosmetic and topical composition, cephalaria oil is provided at a value between 3% and 50% by weight. By means of this, the cosmetic and topical composition provides prevention of the unfavorable effects which result from myristic acid which exists in the body of cosmetic and topical composition.

In a possible embodiment of the present invention, as said diluting component, at least one of water, alcohol and/or diluting oil component is provided with specific weight proportions.

In a possible embodiment of the present invention, the cosmetic and topical composition comprises diluting oil which improves the characteristics of cosmetic and topical composition and which decreases the harmful effects of the cephalaria component in addition to cephalaria oil active substance with specific weight proportions. Said diluting oil is at least one of almond oil, jojoba oil, coconut oil, avocado oil, argan oil, aspir oil, shea oil, sesame oil, lavender oil, camellia oil, rose oil, viola oil, tea seed oil, wheat germ oil, castor oil, inca nut oil, garlic oil, cotton oil, corn oil, orchid oil, olive oil and various other herbal, vegetable and fruit oils.

In a possible embodiment of the present invention, the cosmetic and topical composition is in oil, cream, gel, lotion and sub-dermal injection form.

BRIEF DESCRIPTION OF THE FIGURES

In Figure 1 , the graphic which shows the effect of cephalaria oil concentrations on L929 fibroblast cell viability is given, wherein the horizontal axis shows the cephalaria oil concentrations and the orthogonal axis shows the cell viability increasing % proportions. DETAILED DESCRIPTION OF THE INVENTION

In this detailed description, the subject matter relates to a composition which increases cell viability and which can be used in cosmetic and personal care areas like regenerative cream, care cream, massage oil, humidifier, soap, skin cleaner, lotion, sun cream, ointment, burn cream and is explained with references to examples without forming any restrictive effect only in order to make the subject more understandable.

Said cosmetic and topical composition comprises cephalaria oil with specific weight proportions. The composition moreover comprises a diluting component where at least one of the herbal oils and/or alcohols and/or water is used with specific weight proportions in order to obtain the desired characteristics.

The cephalaria oil comprises pluralities of oil acids for providing usage characteristics in cosmetic and topical products which are to be obtained. Capillary column gas chromatography method has been used for the detection of the composition of oil acids in the cephalaria oil.

Table 1. Weight proportions of the oil acids which exist in cephalaria oil

The ricinoleic acid which exists in the cephalaria oil is the basic component of castor (ricinus communis) oil which eliminates skin problems like acne, fungus, diaper rash, etc. and which prevents inflammation and which provides reinforcing of hair and hair skin. Oil acids like linoleic acid, oleic acid and palmitic acid provided at high proportions in the cephalaria oil are used in skin softening and humidifier products. Linoleic acid and oleic acid are accepted as valuable oil acids for cosmetic and personal care products.

Table 2. Cephalaria oil component analysis

Vitamin E, which exists with proportion of 4.61% by weight in cephalaria oil, is an antioxidant vitamin which can dissolve in oil; and the favorable effects of cephalaria oil in the externally used cosmetic and topical products in oil, cream, gel, lotion and cleaner form is increased.

15-crown-5 substance which exists in the cephalaria oil has binding characteristic on toxic metals. Within this context, usage characteristic is provided to cephalaria oil, which provides cleaning of metal wastes which exist on skin and hair.

It has been determined that cephalaria oil can also be used in burn creams as a result of the studies made within the scope of the present invention in relation to the usage of cephalaria oil in cosmetic and topical products. This usage can be formulized in the form of antibacterial cream which prevents infection (inflammation) of burn injuries and which eliminates aches by showing antiseptic and analgesic effect thanks to the cephalaria oil ingredient. The burn cream with cephalaria oil can be shown as an application example which is suitable for said topical and healing cream usage mentioned in the invention.

Cephalaria oil comprises myristic acid with proportions between 10%-15% by weight. As also known in the art, myristic acid shows high amounts of neurotoxic (having harmful effect on the nerve system) and irritant effect. Therefore, the proportions and concentrations must be adjusted correctly because of the unfavorable effects resulting from myristic acid proportion of cephalaria oil. Thus, in the body of the cosmetic and topical composition to be obtained, there is at least one diluting component which prevents harmful effects of cephalaria oil. The present invention relates to cosmetic and/or topical composition used externally and which is in the form of oil or gel or cream or lotion or oil-based cleaner, and it comprises cephalaria oil, which is decreased to lower than 100%, in the body thereof.

The present invention relates to cosmetic and/or topical composition used externally and which is in the form of oil or gel or cream or lotion or oil-based cleaner; and it comprises cephalaria oil with proportion preferably between 0.7% and 75% by weight in the body thereof. The cosmetic and topical composition comprises cephalaria oil at a value preferably between 3% and 50% by weight in the body thereof. In this form, cephalaria oil where the harmful effects are prevented is used as the active substance.

The present invention relates to usage in cosmetic and personal care areas like regenerative cream, care cream, massage oil, humidifier, soap, skin cleaner, lotion, sun cream, ointment, burn cream. In a preferred application of the present invention, the obtained cosmetic and topical composition is used for the solution of acne, fungus, ageing, inflammation, diaper rash, etc.

According to the present invention, the obtained cosmetic and topical composition can comprise one or more various auxiliary substances in addition to the active substance.

The cosmetic and topical composition comprises herbal oils and/or alcohols and/or water components with specific weight proportions.

According to the present invention, the obtained cosmetic and topical composition can be formulated in solid or liquid dosage forms.

According to the present invention, the obtained cosmetic and topical composition can be formulated in dosage forms which are suitable for receiving by means of dermal way.

In this application, the invention owners present the experimental data which prove the orthogonal axis cell viability increasing percent proportions and the horizontal axis cephalaria oil concentrations and the graphic which shows the effect of the subject matter cephalaria oil concentrations on L929 fibroblast cell viability and the examples related to the production method of the molecule and the data which confirms the cosmetic and topical composition structure obtained in the invention. TESTS

During the development of the present invention, the effect of the different concentrations of cephalaria oil on “L929 fibroblast cell viability” has been researched. The cell viability proportions have been detected for concentrations 1 , 1/2, 1/4, 1/8, 1/16, 1/32, 1/64 and 1/128 of cephalaria oil which exists in the samples. The data obtained in these studies is shown in Figure 1 and Table 3.

Table 3. Illustration of effect of cephalaria oil on cell viability at various concentrations

As shown in Table 3, when the cephalaria oil is used with proportion of 100% (in pure form), it forms an unfavorable effect on cell viability. It is considered that the unfavorable effect of pure cephalaria oil on cell viability is due to myristic acid. The cephalaria oil shows favorable effect on cell viability in the range between 1/2 and 1/128.

As also shown in Figure 1 , cephalaria oil gives the best result on cell viability with concentrations of 1/8 and 1/16. Within this context, cephalaria oil exists at proportions which effect cell viability with the maximum favorable manner since it is included particularly in the range between 3% and 50% by weight in cosmetic and topical products used externally.

EXAMPLES

Some formulations are given below as example to the cosmetic and topical products having cephalaria oil therein. Example 1 - Natural Repairing Cream

Cephalaria oil 36.5% Pure vaseline 26.64%

Aspire oil 18.25% Shea oil 14.60% Vitamin E 4.01%

In the composition obtained by means of the recipe given in Example 1 , the concentration of cephalaria oil has been decreased by means of other oils like aspir and shea. The proportion of cephalaria oil in the natural regenerative cream is provided in the range (lower than 1/2) which provides increase of cell viability as also seen in Figure 1.

Example 2 - Beard Care Oil

Cephalaria oil 45.45%

Jojoba oil 23.38%

Sweet almond oil 23.38%

Vanilla aroma 7.79%

In the composition obtained by means of the recipe given in Example 2, the concentration of cephalaria oil has been decreased by means of other oils like jojoba and sweet almond. The proportion of cephalaria oil in the beard care oil is provided in the range (lower than 1/2) which provides increase of cell viability as also seen in Figure 1.

Example 3 - Flair Care Oil Cephalaria oil 46.15%

Aspire oil 15.38%

Castor oil 15.38%

Sweet almond oil 15.38%

Jojoba oil 4.40%

Viola oil 3.30%

In the composition obtained by means of the recipe given in Example 3, the concentration of cephalaria oil has been decreased by means of other oils like aspir, castor, jojoba, sweet almond and viola. The proportion of cephalaria oil in the hair care oil is provided in the range (lower than 1/2) which provides increase of cell viability as also seen in Figure 1. Example 4 - Massage Oil

Cephalaria oil 75.00% Jojoba oil 8.00% Horse chestnut oil 6.00% Vitamin E 5.00%

Thyme oil 3.00% Tea tree oil 3.00%

The suitable proportion for massage oil has been determined as 75%. When cephalaria oil is used with proportion of 75%, it does not affect cell viability in an unfavorable manner.

The formulations of cosmetic and topical products comprising cephalaria oil and used externally are not limited with the explanations mentioned above. The protection scope of the present invention is set forth in the annexed claims and cannot be restricted to the illustrative disclosures given above, under the detailed description. It is because a person skilled in the relevant art can obviously produce similar embodiments under the light of the foregoing disclosures, without departing from the main principles of the present invention.