Title:
CRYSTALLINE FORMS OF HYDROCHLORIDE SALTS OF THIENOPYRIMIDINE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2017/116192
Kind Code:
A1
Abstract:
The present invention relates to a crystalline form of a hydrochloride salt of N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide, and a pharmaceutical composition containing the same. The crystalline form of the hydrochloride salt of the compound can be easily used for preparing a pharmaceutical composition containing the same as an active ingredient.
Inventors:
BAEK JONG OUK (KR)
JEON JI YOUNG (KR)
OH HEE SOOK (KR)
KIM HEE CHEOL (KR)
JANG SUN YOUNG (KR)
HA TAE HEE (KR)
JEON JI YOUNG (KR)
OH HEE SOOK (KR)
KIM HEE CHEOL (KR)
JANG SUN YOUNG (KR)
HA TAE HEE (KR)
Application Number:
PCT/KR2016/015535
Publication Date:
July 06, 2017
Filing Date:
December 30, 2016
Export Citation:
Assignee:
HANMI PHARM IND CO LTD (KR)
International Classes:
C07D495/04; A61K31/496; A61K31/519; C07D403/10; C07D403/12
Domestic Patent References:
| WO2011162515A2 | 2011-12-29 | |||
| WO2016201370A1 | 2016-12-15 |
Foreign References:
| KR20140118575A | 2014-10-08 | |||
| US20120065233A1 | 2012-03-15 | |||
| US6245759B1 | 2001-06-12 |
Other References:
PHOUJDAR, M. S. ET AL.: "Microwave-based synthesis of novel thienopyrimidine bioisosteres of gefitinib", TETRAHEDRON LETTERS, vol. 49, 2008, pages 1269 - 1273, XP022423221
DATABASE Chemical Abstract 23 June 2016 (2016-06-23), XP055562343, retrieved from REGISTRY Database accession no. 1938072-69-5
See also references of EP 3380481A4
DATABASE Chemical Abstract 23 June 2016 (2016-06-23), XP055562343, retrieved from REGISTRY Database accession no. 1938072-69-5
See also references of EP 3380481A4
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
Download PDF: