Title:
FIBROCARTILAGE-DERIVED BIOINK COMPOSITION, BONE GRAFT COMPOSITION CONTAINING SAME, AND MANUFACTURING METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2024/014892
Kind Code:
A1
Abstract:
The present invention relates to a fibrocartilage-derived bioink composition, a bone graft composition containing same, and a manufacturing method therefore. More specifically, it is identified in the present disclosure that the inner, mid, and outer compartments of the meniscal cartilage tissue based on anatomical location differ from each other in terms of physicochemical property, whereby use is made of the extracellular matrix derived from each compartmentalized tissue to provide 3D-printing bioink compositions and bone grafts, each having distinct physicochemical properties, which can be utilized with controlled physicochemical properties according to desired applications.
Inventors:
PARK DO YOUNG (KR)
YUN HEE-WOONG (KR)
NOH SUJIN (KR)
YUN HEE-WOONG (KR)
NOH SUJIN (KR)
Application Number:
PCT/KR2023/009998
Publication Date:
January 18, 2024
Filing Date:
July 13, 2023
Export Citation:
Assignee:
UNIV AJOU IND ACADEMIC COOP FOUND (KR)
International Classes:
A61L27/56; A61L27/36
Foreign References:
| KR20180125776A | 2018-11-26 | |||
| KR20200003304A | 2020-01-09 |
Other References:
CHAE SUHUN, LEE SUNG-SAHN, CHOI YEONG-JIN, HONG DA HEE, GAO GE, WANG JOON HO, CHO DONG-WOO: "3D cell-printing of biocompatible and functional meniscus constructs using meniscus‐derived bioink", BIOMATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 267, 1 January 2021 (2021-01-01), AMSTERDAM, NL , pages 120466, XP093127161, ISSN: 0142-9612, DOI: 10.1016/j.biomaterials.2020.120466
YUN HEE-WOONG; SONG BO RAM; SHIN DONG IL; YIN XIANG YUN; TRUONG MINH-DUNG; NOH SUJIN; JIN YOUNG JUN; KWON HYEON JAE; MIN BYOUNG-HY: "Fabrication of decellularized meniscus extracellular matrix according to inner cartilaginous, middle transitional, and outer fibrous zones result in zone-specific protein expression useful for precise replication of meniscus zones", MATERIALS SCIENCE AND ENGINEERING C, ELSEVIER SCIENCE S.A., CH, vol. 128, 14 July 2021 (2021-07-14), CH , XP086757719, ISSN: 0928-4931, DOI: 10.1016/j.msec.2021.112312
DRISCOLL J. ADAM, LUBBE RYAN, JAKUS ADAM E., CHANG KEVIN, HALEEM MERAAJ, YUN CHAWON, SINGH GURMIT, SCHNEIDER ANDREW D., KATCHKO KA: "3D-Printed Ceramic-Demineralized Bone Matrix Hyperelastic Bone Composite Scaffolds for Spinal Fusion", TISSUE ENGINEERING PART A, MARY ANN LIEBERT, US, vol. 26, no. 3-4, 1 February 2020 (2020-02-01), US , pages 157 - 166, XP093071398, ISSN: 1937-3341, DOI: 10.1089/ten.tea.2019.0166
YUN HEE-WOONG; SONG BO RAM; SHIN DONG IL; YIN XIANG YUN; TRUONG MINH-DUNG; NOH SUJIN; JIN YOUNG JUN; KWON HYEON JAE; MIN BYOUNG-HY: "Fabrication of decellularized meniscus extracellular matrix according to inner cartilaginous, middle transitional, and outer fibrous zones result in zone-specific protein expression useful for precise replication of meniscus zones", MATERIALS SCIENCE AND ENGINEERING C, ELSEVIER SCIENCE S.A., CH, vol. 128, 14 July 2021 (2021-07-14), CH , XP086757719, ISSN: 0928-4931, DOI: 10.1016/j.msec.2021.112312
DRISCOLL J. ADAM, LUBBE RYAN, JAKUS ADAM E., CHANG KEVIN, HALEEM MERAAJ, YUN CHAWON, SINGH GURMIT, SCHNEIDER ANDREW D., KATCHKO KA: "3D-Printed Ceramic-Demineralized Bone Matrix Hyperelastic Bone Composite Scaffolds for Spinal Fusion", TISSUE ENGINEERING PART A, MARY ANN LIEBERT, US, vol. 26, no. 3-4, 1 February 2020 (2020-02-01), US , pages 157 - 166, XP093071398, ISSN: 1937-3341, DOI: 10.1089/ten.tea.2019.0166
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
Download PDF: