GENETICALLY MODIFIED CLOSTRIDIUM SACCHAROPERBUTYLACETONICUM

Title:

GENETICALLY MODIFIED CLOSTRIDIUM SACCHAROPERBUTYLACETONICUM

Document Type and Number:

WIPO Patent Application WO/2014/156476

Kind Code:

A1

Abstract:

Provided is a means for highly efficiently generating butanol in butanol fermentation. The present invention pertains to: a genetically modified Clostridium saccharoperbutylacetonicum microbe; and a method for producing butanol using the microbe.

Inventors:

DOBASHI YUKIO (JP)
MUKOYAMA MASAHARU (JP)
ICHIGE EITA (JP)
NAKANOSHO MASAHIRO (JP)
NAKAYAMA SHUNICHI (JP)

Application Number:

PCT/JP2014/055140

Publication Date:

October 02, 2014

Filing Date:

February 28, 2014

Export Citation:

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Assignee:

NIPPON CATALYTIC CHEM IND (JP)

International Classes:

C12N1/21; C12P7/16; C12N15/09; C12R1/145

Domestic Patent References:

WO2011099165A1

2011-08-18

Foreign References:

CN101519673A

2009-09-02

Other References:

E. M. GREEN ET AL.: "Genetic manipulation of acid formation pathways by gene inactivation in Clostridium acetobutylicum ATCC 824", MICROBIOLOGY, vol. 142, 1996, pages 2079 - 2086
C. M. COOKSLEY ET AL.: "Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol- ethanol fermentation pathway", METABOLIC ENGINEERING, vol. 14, 2012, pages 630 - 641
Y. TASHIRO ET AL.: "High Butanol Production by Clostridium saccharoperbutylacetonicum N1-4 in Fed-Batch Culture with pH-Stat Continuous Butyric Acid and Glucose Feeding Method", JOURNAL OF BIOSCIENCE AND BIOENGINEERING, vol. 98, no. 4, 2004, pages 263 - 268