Title:
GLASS COMPOSITES FOR TISSUE AUGMENTATION, BIOMEDICAL AND COSMETIC APPLICATIONS
Document Type and Number:
WIPO Patent Application WO/2016/090359
Kind Code:
A3
Abstract:
Compositions and methods for glass composites suitable for tissue augmentation, biomedical, and cosmetic applications are provided. The glass microsphere component of the composites are biologically inert, non-reactive and act as a nearly permanent tissue filler. One embodiment provides a tissue augmentation composite containing an effective amount of solid glass microspheres, hollow glass microspheres, porous wall hollow glass microspheres, or combinations thereof with a suitable biocompatible matrix to serve as a bulking agent when injected into a patient. The compositions can be used for soft or hard tissue augmentation as well as delivery of cargos on demand.
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Inventors:
WEINBERGER PAUL M (US)
HILL WILLIAM D (US)
WICKS GEORGE G (US)
HILL WILLIAM D (US)
WICKS GEORGE G (US)
Application Number:
PCT/US2015/064252
Publication Date:
September 15, 2016
Filing Date:
December 07, 2015
Export Citation:
Assignee:
AUGUSTA UNIV RES INST INC (US)
APPLIED RES CENTER INC
APPLIED RES CENTER INC
International Classes:
A61Q19/08; A61K8/02
Domestic Patent References:
| WO2000030561A1 | 2000-06-02 | |||
| WO2011008939A2 | 2011-01-20 |
Foreign References:
| DE102004021700A1 | 2005-11-24 | |||
| EP0251695A2 | 1988-01-07 | |||
| US20080035020A1 | 2008-02-14 |
Other References:
LI S ET AL: "Porous-wall hollow glass microspheres as novel potential nanocarriers for biomedical applications", NANOMEDICINE: NANOTECHNOLOGY, BIOLOGY AND MEDICINE, ELSEVIER, NL, vol. 6, no. 1, 1 February 2010 (2010-02-01), pages 127 - 136, XP027501943, ISSN: 1549-9634, [retrieved on 20100201], DOI: 10.1016/J.NANO.2009.06.004
Attorney, Agent or Firm:
PABST, Patrea, L. et al. (1545 Peachtree Street N.E., Suite 32, Atlanta GA, US)
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