Title:
GLYCEROL DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2004/029018
Kind Code:
A1
Abstract:
A compound represented by the following formula (1): (1) wherein R represents a residue having either a reactive group or a group capable of changing into a reactive group; n is an integer of 3 or larger; X represents a residue capable of having n groups of the formula (2) and the six or more R1's are the same or different and each represents hydrogen or a group capable of changing into hydrogen. The compound can chemically modify physiologically active polypeptides, derivatives thereof, or low-molecular compounds, while maintaining the physiological activity thereof. The compound is useful for improving the stability or water solubility of low-molecular compounds.
Inventors:
NEMOTO HISAO (JP)
YAMASAKI MOTOO (JP)
SUZAWA TOSHIYUKI (JP)
YAMAGUCHI HIROYUKI (JP)
YAMASAKI MOTOO (JP)
SUZAWA TOSHIYUKI (JP)
YAMAGUCHI HIROYUKI (JP)
Application Number:
PCT/JP2003/011214
Publication Date:
April 08, 2004
Filing Date:
September 02, 2003
Export Citation:
Assignee:
KYOWA HAKKO KOGYO KK (JP)
TECNO NETWORK SHIKOKU CO LTD (JP)
NEMOTO HISAO (JP)
YAMASAKI MOTOO (JP)
SUZAWA TOSHIYUKI (JP)
YAMAGUCHI HIROYUKI (JP)
TECNO NETWORK SHIKOKU CO LTD (JP)
NEMOTO HISAO (JP)
YAMASAKI MOTOO (JP)
SUZAWA TOSHIYUKI (JP)
YAMAGUCHI HIROYUKI (JP)
International Classes:
A61K47/48; A61P43/00; C07C233/78; C07C237/22; C07C323/60; C07D207/404; C07D207/40; (IPC1-7): C07C233/47; C07C323/52; C07D207/404; C07K14/53; C12N9/00; A61K38/00; A61K38/27; A61K38/28; A61K38/43; A61K38/48; A61K39/395; A61K47/48; A61P43/00
Other References:
MALENFANT PATRICK R.L. ET AL: "Dendrimers as Solubilizing Groups for Conducting Polymers : Preparation and Characterization of Polythiophene Functionalizated Exclusively with Alipathic Ether Convergent Dendrons.", MACROMOLECULES, vol. 33, no. 10, 2000, pages 3634 - 3640, XP002975849
MALENFANT PATRICK R.L. ET AL: "Dendrimer-Supported Oligothiophene Synthesis : Alipathic Ether Dendrimers in the Preparation of Oligothiophenes with Minimal Substitution.", CHEMISTRY OF MATERIALS, vol. 11, no. 12, 1999, pages 3420 - 3422, XP000919552
MALENFANT PATRICK R.L. ET AL: "Dendrimer-supported solution synthesis of oligothiophenes without beta substituents.", POLYMERIC MATERIALS SCIENCE AND ENGINEERING, no. 80, 1999, pages 171 - 172, XP002975850
MALENFANT PATRICK R.L. ET AL: "Dendrimer-Supported Oligothiophene Synthesis : Alipathic Ether Dendrimers in the Preparation of Oligothiophenes with Minimal Substitution.", CHEMISTRY OF MATERIALS, vol. 11, no. 12, 1999, pages 3420 - 3422, XP000919552
MALENFANT PATRICK R.L. ET AL: "Dendrimer-supported solution synthesis of oligothiophenes without beta substituents.", POLYMERIC MATERIALS SCIENCE AND ENGINEERING, no. 80, 1999, pages 171 - 172, XP002975850
Attorney, Agent or Firm:
Oguri, Shohei (13th Floor ARK Mori Building, 12-32, Akasaka 1-chom, Minato-ku Tokyo, JP)
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