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Title:
HEPATITIS A VIRUS PREPARATION METHOD AND HEPATITIS A VIRUS PREPARED ACCORDING TO METHOD
Document Type and Number:
WIPO Patent Application WO/2021/125891
Kind Code:
A1
Abstract:
The present invention relates to a hepatitis A virus production method and hepatitis A virus produced according to the method, and, more specifically, to: a hepatitis A virus production method and hepatitis A virus produced according to the method, the method comprising the step of infecting a host cell with a virus obtained by transforming a host cell with a vector comprising an expression cassette, which comprises a hepatitis A virus gene, for hepatitis A virus preparation, and subculturing same.

Inventors:
LEE JUNG-EUN (KR)
KIM SOO-YOUNG (KR)
CHO SEO YOUNG (KR)
KIM HUN (KR)
LEE KUN SE (KR)
LEE SUJEEN (KR)
Application Number:
PCT/KR2020/018703
Publication Date:
June 24, 2021
Filing Date:
December 18, 2020
Export Citation:
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Assignee:
SK BIOSCIENCE CO LTD (KR)
International Classes:
C12N15/86; A61K39/29; C12N7/00
Foreign References:
US6680060B22004-01-20
US5731187A1998-03-24
KR20150136767A2015-12-08
KR20190171279A2019-12-19
US6423318B12002-07-23
US5057540A1991-10-15
Other References:
DATABASE Genbank 21 June 2017 (2017-06-21), ANONYMOUS: "Hepatitis A virus isolate 18f, complete genome. 21 June 2017. See entire document. A 1-23", XP009528608, retrieved from NCBI Genbank Database accession no. KP879216.1
TAN CHEE WAH, TEE HAN KANG, LEE MICHELLE HUI PHENG, SAM I-CHING, CHAN YOKE FUN: "Enterovirus A71 DNA-Launched Infectious Clone as a Robust Reverse Genetic Tool", PLOS ONE, vol. 11, no. 9, pages e0162771, XP055823461, DOI: 10.1371/journal.pone.0162771
SM LEMON ET AL., J. HEPATOL, vol. 68, no. 1, 2018, pages 167 - 184
TOTSUKAMORITSUGU, INTERVIROLOGY, vol. 42, 1999, pages 63 - 68
NWACHUKUGERBA, REV. ENVIRON. CONTAM. TOXICOL., vol. 186, 2006, pages 1 - 56
KIMLEE, INTERVIROLOGY, vol. 53, no. 1, 2010, pages 10 - 14
KOREA CENTERS FOR DISEASE CONTROL AND PREVENTION, INFECTIOUS DISEASES PORTAL LEGAL INFECTIOUS DISEASE STATISTICS BY DISEASE - HEPATITIS A
NELSON NPWENG MKHOFMEISTER MG ET AL.: "Prevention of Hepatitis A Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices", MMWR RECOMM REP, vol. 69, no. RR-5, 2020, pages 1 - 38
CROMEANS ET AL., J. GEN. VIROL, vol. 70, 1989, pages 2051 - 2062
T. CROMEANS ET AL., J MEDICAL VIROLOGY, vol. 22, 1987, pages 45 - 56
JORDANSANDIG, VIRUSES, vol. 6, 2014, pages 1672 - 1700
EDISON, N. J., NEW BRUNSWICK SCIENTIFIC
See also references of EP 4079859A4
Attorney, Agent or Firm:
LEE, Hee Sook (KR)
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