Title:
HETEROARYL DERIVATIVE AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/140640
Kind Code:
A1
Abstract:
The present invention relates to a heteroaryl derivative, a stereoisomer thereof, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof, a method for preparing same, and a pharmaceutical composition for preventing or treating cancer comprising same as an active ingredient. The heteroaryl derivative of the present invention exhibits high inhibitory activity against overexpressed HER2, and thus, a pharmaceutical composition containing the heteroaryl derivative as an active ingredient can be particularly useful for preventing or treating HER2-positive cancer.
More Like This:
| WO/2002/087700 | METHOD, KIT AND DEVICE FOR THE TREATMENT OF COSMETIC SKIN CONDITIONS |
| WO/2010/080306 | PURINE COMPOUNDS |
| JPH11504313 | [Title of Invention] A novel pharmaceutical composition |
Inventors:
KONG GU (KR)
KUCHUKULLA RATNAKAR REDDY (KR)
KIM SU MIN (KR)
MOON SO JEONG (KR)
HUR WOO YOUNG (KR)
HWANG IN JEONG (KR)
KUCHUKULLA RATNAKAR REDDY (KR)
KIM SU MIN (KR)
MOON SO JEONG (KR)
HUR WOO YOUNG (KR)
HWANG IN JEONG (KR)
Application Number:
PCT/KR2023/000930
Publication Date:
July 27, 2023
Filing Date:
January 19, 2023
Export Citation:
Assignee:
IUCF HYU (KR)
KOREA INST SCI & TECH (KR)
KOREA INST SCI & TECH (KR)
International Classes:
A61K31/52; C07D473/34; A61K31/537; A61P35/00
Domestic Patent References:
| WO2014121764A2 | 2014-08-14 | |||
| WO1998005335A1 | 1998-02-12 |
Foreign References:
| US20020091263A1 | 2002-07-11 |
Other References:
JOANNAH NGOMPAZA-DIARRA; KARIMA BETTAYEB; NOHAD GRESH; LAURENT MEIJER; NASSIMA OUMATA;: "Synthesis and biological evaluation of selective and potent cyclin-dependent kinase inhibitors", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 56, 22 August 2012 (2012-08-22), AMSTERDAM, NL , pages 210 - 216, XP028516175, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2012.08.033
TROVA, M.P. ; BARNES, K.D. ; BARFORD, C. ; BENANTI, T. ; BIELASKA, M. ; BURRY, L. ; LEHMAN, J.M. ; MURPHY, C. ; OGRADY, H. ;: "Biaryl purine derivatives as potent antiproliferative agents: Inhibitors of cyclin dependent kinases. Part I", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ELSEVIER, AMSTERDAM NL, vol. 19, no. 23, 1 December 2009 (2009-12-01), Amsterdam NL , pages 6608 - 6612, XP026736067, ISSN: 0960-894X, DOI: 10.1016/j.bmcl.2009.10.025
TROVA, M.P. ; BARNES, K.D. ; BARFORD, C. ; BENANTI, T. ; BIELASKA, M. ; BURRY, L. ; LEHMAN, J.M. ; MURPHY, C. ; OGRADY, H. ;: "Biaryl purine derivatives as potent antiproliferative agents: Inhibitors of cyclin dependent kinases. Part I", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ELSEVIER, AMSTERDAM NL, vol. 19, no. 23, 1 December 2009 (2009-12-01), Amsterdam NL , pages 6608 - 6612, XP026736067, ISSN: 0960-894X, DOI: 10.1016/j.bmcl.2009.10.025
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
Download PDF: