Title:
HETEROCYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/037631
Kind Code:
A1
Abstract:
The present invention relates to a heterocyclic derivative and a preparation method therefor and use thereof in medicine. Specifically, the present invention relates to a heterocyclic derivative represented by general formula (I), a preparation method therefor and a pharmaceutically acceptable salt thereof, and use thereof as therapeutic agents, especially as K-Ras GTPase inhibitors, wherein the definition of substituents in the general formula (I) is the same as the definition in the description.
Inventors:
CHEN YOUXI (CN)
CHENG CHAOYING (CN)
GONG LIANG (CN)
MAO WENTAO (CN)
XIANG QING (CN)
ZHAO WEIFENG (CN)
ZHAO WENWEN (CN)
HE YANLING (CN)
ZHU MINGJIANG (CN)
YE CHENG (CN)
HU TAISHAN (CN)
QIAN WENJIAN (CN)
CHEN LEI (CN)
CHENG CHAOYING (CN)
GONG LIANG (CN)
MAO WENTAO (CN)
XIANG QING (CN)
ZHAO WEIFENG (CN)
ZHAO WENWEN (CN)
HE YANLING (CN)
ZHU MINGJIANG (CN)
YE CHENG (CN)
HU TAISHAN (CN)
QIAN WENJIAN (CN)
CHEN LEI (CN)
Application Number:
PCT/CN2021/113453
Publication Date:
February 24, 2022
Filing Date:
August 19, 2021
Export Citation:
Assignee:
ZHEJIANG HISUN PHARM CO LTD (CN)
HISUN ACCURAY THERAPEUTICS CO LTD (CN)
HISUN ACCURAY THERAPEUTICS CO LTD (CN)
International Classes:
C07D471/04; A61K31/4162; A61K31/519; A61P35/00; C07D471/14
Domestic Patent References:
| WO2019209896A1 | 2019-10-31 | |||
| WO2019047824A1 | 2019-03-14 |
Foreign References:
| CN101742908A | 2010-06-16 |
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
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