Title:
HIGH-CONCENTRATION LIDOCAINE COMPOSITIONS AND METHODS FOR THEIR PREPARATION
Document Type and Number:
WIPO Patent Application WO2003041648
Kind Code:
A3
Abstract:
A composition comprising lidocaine-containing liposomes wherein the weight concentration of lidocaine in said composition is greater than 10 %. The composition is prepared by mixing water with an oil phase comprising lidocaine, a C14-C20 alcohol, an alkyl ester of a fatty acid, propylene glycol, and a polyalkyl stearate. The non-aqueous phase may also include a phospholipid such as phosphatidyl choline.
Inventors:
PATEL PRAVIN M (US)
Application Number:
PCT/US2002/036349
Publication Date:
November 13, 2003
Filing Date:
November 13, 2002
Export Citation:
Assignee:
FERNDALE LAB INC (US)
PATEL PRAVIN M (US)
PATEL PRAVIN M (US)
International Classes:
A61K9/00; A61K31/165; A61K9/127; A61K31/167; A61K47/10; A61K47/14; A61K47/22; A61K47/24; A61K47/34; A61P23/02; (IPC1-7): A61K9/127; A61K31/16
Foreign References:
| US5490985A | 1996-02-13 | |||
| US5439967A | 1995-08-08 | |||
| US4937078A | 1990-06-26 |
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