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Title:
HIGH-SPEED SCREENING APPARATUS FOR A RAMAN ANALYSIS-BASED HIGH-SPEED MULTIPLE DRUG
Document Type and Number:
WIPO Patent Application WO/2012/165837
Kind Code:
A2
Abstract:
The present invention relates to a high-speed screening apparatus for a raman analysis-based high-speed multiple drug. The screening apparatus according to the present invention may easily detect a raman signal using a core-cap-shell nanoparticle which amplifies the raman signal by 1012 times and has high reproducibility through raman spectroscopy in which materials do not interfere with each other and a spectrum has a sharp peak to detect the raman signal multiple times. Also, since a CCD camera, not a scanner, may be used as the detector, the screening apparatus may multiply screen the drug at a high speed without movement between molecules within a sample. In addition, since multicolors of 5 colors or more may be coated, the screening apparatus may be usefully used for screening various drugs.

Inventors:
SUH YUNG DOUG (KR)
JEON KI SEOK (KR)
KIM HYUNG MIN (KR)
LEE KANG TAEK (KR)
JIN SEUNG MIN (KR)
NAM SANG HWAN (KR)
BAE YUN MI (KR)
LEE HAEMI (KR)
LEE KYUNGHEE (KR)
PARK HYO SUN (KR)
KIM PHIL HWAN (KR)
Application Number:
PCT/KR2012/004223
Publication Date:
December 06, 2012
Filing Date:
May 29, 2012
Export Citation:
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Assignee:
KOREA RES INST CHEM TECH (KR)
SUH YUNG DOUG (KR)
JEON KI SEOK (KR)
KIM HYUNG MIN (KR)
LEE KANG TAEK (KR)
JIN SEUNG MIN (KR)
NAM SANG HWAN (KR)
BAE YUN MI (KR)
LEE HAEMI (KR)
LEE KYUNGHEE (KR)
PARK HYO SUN (KR)
KIM PHIL HWAN (KR)
International Classes:
G01N33/15; G01N21/65; G01N33/52; G01N33/53
Foreign References:
KR20100002742A2010-01-07
JP2007502716A2007-02-15
US6643012B22003-11-04
JP2008241640A2008-10-09
Other References:
SCIENCE, vol. 275, no. 5303, 1997, pages 1102
PHYS REV LETT, vol. 78, no. 9, 1997, pages 1667
SCIENCE, vol. 297, 2002, pages 1536
J PHYS CHEM B, vol. 106, no. 2, 2002, pages 311
SCIENCE, vol. 321, 2008, pages 388
S. J. HURST; A. K. R. LYTTON-JEAN; C. A. MIRKIN, ANAL. CHEM., vol. 78, 2006, pages 8313
W. PETER WUELFING; STEPHEN M. GROSS; DEON T. MILES; ROYCE W. MURRAY, J. AM. CHEM. SOC., vol. 120, 1998, pages 12696
See also references of EP 2717052A4
Attorney, Agent or Firm:
LEE, Won Hee (642-16 Yoksam-dong, Kangnam-ku, Seoul 135-080, KR)
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Claims: