Title:
HUMAN POLYNUCLEOTIDES AND POLYPEPTIDES ENCODED THEREBY
Document Type and Number:
WIPO Patent Application WO2002024733
Kind Code:
A3
Abstract:
Disclosed herein are nucleic acid sequences that encode Wnt, zinc transporter, mitsugumin29, slit-3, LRR/GPCR, major histocompatibility complex enhancer protein MAD3, interleukin 9, 5-hydroxytryptamine receptor, and thioredoxin related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Inventors:
MISHRA VISHNU S (US)
SPYTEK KIMBERLY ANN (US)
TAUPIER RAYMOND J JR (US)
VERNET CORINE A M (US)
COLMAN STEVEN D (US)
GORMAN LINDA (US)
TCHERNEV VELIZAR T (US)
MALYANKAR URIEL M (US)
SHENOY SURESH (US)
PADIGARU MURALIDHARA (US)
PATTURAJAN MEERA (US)
BURGESS CATHERINE E (US)
SMITHSON GLENNDA (US)
MILLET ISABELLE (US)
PEYMAN JOHN A (US)
STONE DAVID (US)
GUNTHER ERIK (US)
ELLERMAN KAREN (US)
SPYTEK KIMBERLY ANN (US)
TAUPIER RAYMOND J JR (US)
VERNET CORINE A M (US)
COLMAN STEVEN D (US)
GORMAN LINDA (US)
TCHERNEV VELIZAR T (US)
MALYANKAR URIEL M (US)
SHENOY SURESH (US)
PADIGARU MURALIDHARA (US)
PATTURAJAN MEERA (US)
BURGESS CATHERINE E (US)
SMITHSON GLENNDA (US)
MILLET ISABELLE (US)
PEYMAN JOHN A (US)
STONE DAVID (US)
GUNTHER ERIK (US)
ELLERMAN KAREN (US)
Application Number:
PCT/US2001/029115
Publication Date:
July 03, 2003
Filing Date:
September 17, 2001
Export Citation:
Assignee:
CURAGEN CORP (US)
MISHRA VISHNU S (US)
SPYTEK KIMBERLY ANN (US)
TAUPIER RAYMOND J JR (US)
VERNET CORINE A M (US)
COLMAN STEVEN D (US)
GORMAN LINDA (US)
TCHERNEV VELIZAR T (US)
MALYANKAR URIEL M (US)
SHENOY SURESH (US)
PADIGARU MURALIDHARA (US)
PATTURAJAN MEERA (US)
BURGESS CATHERINE E (US)
SMITHSON GLENNDA (US)
MILLET ISABELLE (US)
PEYMAN JOHN A (US)
STONE DAVID (US)
GUNTHER ERIK (US)
ELLERMAN KAREN (US)
MISHRA VISHNU S (US)
SPYTEK KIMBERLY ANN (US)
TAUPIER RAYMOND J JR (US)
VERNET CORINE A M (US)
COLMAN STEVEN D (US)
GORMAN LINDA (US)
TCHERNEV VELIZAR T (US)
MALYANKAR URIEL M (US)
SHENOY SURESH (US)
PADIGARU MURALIDHARA (US)
PATTURAJAN MEERA (US)
BURGESS CATHERINE E (US)
SMITHSON GLENNDA (US)
MILLET ISABELLE (US)
PEYMAN JOHN A (US)
STONE DAVID (US)
GUNTHER ERIK (US)
ELLERMAN KAREN (US)
International Classes:
G01N33/50; A61B10/00; A61B10/02; A61K38/00; A61K39/395; A61K48/00; A61P35/00; C07K14/47; C07K14/475; C07K14/54; C07K14/705; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12N15/24; C12P21/08; C12Q1/02; C12Q1/68; G01N33/15; G01N33/53; G01N33/566; A61B17/00; (IPC1-7): C12N15/12; A61K31/7088; A61K38/17; A61K38/19; A61K38/44; A61K39/00; C07K14/47; C07K14/475; C07K14/54; C07K14/705; C07K16/18; C07K16/24; C07K16/28; C07K16/40; C12N9/02; C12N15/11; C12N15/24; C12N15/53; C12N15/62; C12Q1/68; G01N33/68; A61K67/027; C07K16/72
Domestic Patent References:
| WO1999057248A1 | 1999-11-11 |
Foreign References:
| EP0887408A1 | 1998-12-30 |
Other References:
DATABASE SWALL [online] 15 July 1999 (1999-07-15), XP002220483, retrieved from EBI Database accession no. P56704
DATABASE SWALL [online] 1 August 1992 (1992-08-01), XP002220486, retrieved from EBI Database accession no. P27467
DATABASE EMBL [online] 22 May 1991 (1991-05-22), XP002220487, retrieved from EBI Database accession no. X56842
HUGUET E L ET AL: "Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 54, no. 10, 15 May 1994 (1994-05-15), pages 2615 - 2621, XP002121611, ISSN: 0008-5472
DATABASE SWALL [online] 1 August 1992 (1992-08-01), XP002220486, retrieved from EBI Database accession no. P27467
DATABASE EMBL [online] 22 May 1991 (1991-05-22), XP002220487, retrieved from EBI Database accession no. X56842
HUGUET E L ET AL: "Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 54, no. 10, 15 May 1994 (1994-05-15), pages 2615 - 2621, XP002121611, ISSN: 0008-5472
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