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Title:
IMPLANTABLE BIOARTIFICIAL PERFUSION SYSTEM
Document Type and Number:
WIPO Patent Application WO/2013/163375
Kind Code:
A3
Abstract:
The disclosure provides an implantable bioartificial active secretion system for providing a physiological regulating secretion such as insulin necessary for functionality of a physiologic activity such as glucose metabolism of a living-being host. The system includes a housing implantable within the host, in fluidic communication with tissue fluid indicative of a physiological regulating secretion need. A chamber within the housing contains a plurality of physiologically active, autonomously functioning, live secretory cells for producing the physiological regulating secretion. A continually operating two pump apparatus moves tissue fluid into contact with the secretory cells for pick up of the physiological regulating secretion for subsequent physiologically-effective dispensing into the host, while avoiding immunorejection of the host body or of the host to the secretory cells.

Inventors:
ZELTSER GREGORY (US)
PILIAVIN MICHAEL (US)
Application Number:
PCT/US2013/038133
Publication Date:
February 20, 2014
Filing Date:
April 25, 2013
Export Citation:
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Assignee:
ZELTSER GREGORY (US)
PILIAVIN MICHAEL (US)
International Classes:
A61K9/22
Domestic Patent References:
WO1998050088A11998-11-12
WO2011085180A22011-07-14
Foreign References:
US20020103475A12002-08-01
US20090041825A12009-02-12
US5141631A1992-08-25
US20110142700A12011-06-16
Other References:
See also references of EP 2841059A4
Attorney, Agent or Firm:
ROBINSON, Edward D. et al. (1345 Encinitas Boulevard Suite 44, Encinitas California, US)
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