Title:
IN VIVO FLUORINATION
Document Type and Number:
WIPO Patent Application WO/2020/083958
Kind Code:
A3
Abstract:
The present invention relates to a cell capable of producing a fluorinated, a chlorinated or a brominated compound, methods for producing fluorinated, chlorinated or brominated compounds in a cell and expression systems therefor.
Inventors:
NIKEL PABLO (DK)
VALDAYO PATRICIA (DK)
VALDAYO PATRICIA (DK)
Application Number:
PCT/EP2019/078790
Publication Date:
July 23, 2020
Filing Date:
October 23, 2019
Export Citation:
Assignee:
UNIV DANMARKS TEKNISKE (DK)
International Classes:
C12P19/40; C12N9/10
Domestic Patent References:
| WO2012153142A2 | 2012-11-15 | |||
| WO2013040548A2 | 2013-03-21 |
Other References:
ANON.: "Testing for the Effect of Fluoride on CHOP on E. coli Growth at Different Concentrations of Chloramphenicol", 7 January 2018 (2018-01-07), XP002797876, Retrieved from the Internet [retrieved on 20200224]
DATABASE UniProt [online] 18 July 2018 (2018-07-18), DENG, H. ET AL.: "Full=Fluorinase", XP002791028, Database accession no. W0W999
ASHTON, T.D. ET AL.: "An improved synthesis of 5'-fluoro-5'-deoxyadenosines", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, no. 14, 15 July 2005 (2005-07-15), pages 3361 - 3363, XP027801580
DATABASE UniProt [online] 18 July 2018 (2018-07-18), DENG, H. ET AL.: "Full=Fluorinase", XP002791028, Database accession no. W0W999
ASHTON, T.D. ET AL.: "An improved synthesis of 5'-fluoro-5'-deoxyadenosines", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 15, no. 14, 15 July 2005 (2005-07-15), pages 3361 - 3363, XP027801580
Attorney, Agent or Firm:
HØIBERG P/S (DK)
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