Title:
INDOLINONE HYDRAZIDES AS C-MET INHIBITORS
Document Type and Number:
WIPO Patent Application WO2005005378
Kind Code:
A3
Abstract:
The present invention relates to compounds of the formulae (I) - (XII), wherein R1 - R71, A, B, X, Y, G, L and Z are defined herein, and their pharmaceutically acceptable salts. These compounds modulate the activity of c-Met and are therefore expected to be useful in the prevention and treatment of c-Met related disorders such as cancer.
Inventors:
KOENIG MARCEL (US)
CUI JINGRONG (US)
WEI CHUNG CHEN (US)
DO STEVEN HUY (US)
ZHANG FANG-JIE (US)
VOJKOVSKY TOMAS (US)
RAMPHAL JOHN (US)
YANG GUANG (US)
MATTSON MATTHEW (US)
NELSON CHRISTOPHER (US)
TANG PENG CHO (US)
CUI JINGRONG (US)
WEI CHUNG CHEN (US)
DO STEVEN HUY (US)
ZHANG FANG-JIE (US)
VOJKOVSKY TOMAS (US)
RAMPHAL JOHN (US)
YANG GUANG (US)
MATTSON MATTHEW (US)
NELSON CHRISTOPHER (US)
TANG PENG CHO (US)
Application Number:
PCT/US2004/017423
Publication Date:
March 03, 2005
Filing Date:
June 25, 2004
Export Citation:
Assignee:
SUGEN INC (US)
KOENIG MARCEL (US)
CUI JINGRONG (US)
WEI CHUNG CHEN (US)
DO STEVEN HUY (US)
ZHANG FANG-JIE (US)
VOJKOVSKY TOMAS (US)
RAMPHAL JOHN (US)
YANG GUANG (US)
MATTSON MATTHEW (US)
NELSON CHRISTOPHER (US)
TANG PENG CHO (US)
KOENIG MARCEL (US)
CUI JINGRONG (US)
WEI CHUNG CHEN (US)
DO STEVEN HUY (US)
ZHANG FANG-JIE (US)
VOJKOVSKY TOMAS (US)
RAMPHAL JOHN (US)
YANG GUANG (US)
MATTSON MATTHEW (US)
NELSON CHRISTOPHER (US)
TANG PENG CHO (US)
International Classes:
C07D403/12; C07D; (IPC1-7): C07D403/12
Foreign References:
| US4616009A | 1986-10-07 |
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