Title:
ISOLATED HUMAN PHOSPHODIESTERASE PROTEINS, NUCLEIC ACID MOLECULES ENCODING HUMAN PHOSPHODIESTERASE PROTEINS, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2002053718
Kind Code:
A3
Abstract:
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phosphodiesterase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phosphodiesterase peptides, and methods of identifying modulators of the phosphodiesterase peptides.
Inventors:
WEI MING-HUI
WANG XIN
MERKULOV GENNADY
DI FRANCESCO VALENTINA
BEASLEY ELLEN M
WANG XIN
MERKULOV GENNADY
DI FRANCESCO VALENTINA
BEASLEY ELLEN M
Application Number:
PCT/US2002/000134
Publication Date:
May 15, 2003
Filing Date:
January 02, 2002
Export Citation:
Assignee:
PE CORP NY (US)
International Classes:
C12N9/16; C12N15/55; (IPC1-7): C12N9/16; C12N15/55; C07K16/40; C12N5/10; C12N15/79; C12Q1/68; A01K67/027
Domestic Patent References:
| WO2001059155A2 | 2001-08-16 | |||
| WO1992018541A1 | 1992-10-29 | |||
| WO1995011995A1 | 1995-05-04 |
Other References:
ROSMAN G J ET AL: "ISOLATION AND CHARATERIZATION OF HUMAN CDNAS ENCODING A CGMP-STIMULATED 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 191, 1997, pages 89 - 95, XP002938026, ISSN: 0378-1119
DATABASE EBI [online] XP002231139, retrieved from EMBL Database accession no. AC023176
DATABASE EBI [online] XP002231140, retrieved from EMBL Database accession no. AC026173
GRAEME B BOLGER ET AL: "Differential CNS expression of alternative isoforms of the mammalian genes encoding cAMP-specific phosphodiesterases", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 149, no. 2, 1994, pages 237 - 244, XP002150452, ISSN: 0378-1119
DATABASE EBI [online] XP002231139, retrieved from EMBL Database accession no. AC023176
DATABASE EBI [online] XP002231140, retrieved from EMBL Database accession no. AC026173
GRAEME B BOLGER ET AL: "Differential CNS expression of alternative isoforms of the mammalian genes encoding cAMP-specific phosphodiesterases", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 149, no. 2, 1994, pages 237 - 244, XP002150452, ISSN: 0378-1119
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