Title:
ISOXAZOLIDINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS
Document Type and Number:
WIPO Patent Application WO2006009907
Kind Code:
A3
Abstract:
The present invention relates to antibiotic compounds and intermediates useful in their preparation. Many of the antibiotic compounds contain a substituted isoxazolidine ring. The invention also relates to pharmaceutical compositions containing a compound of the invention. The invention further provides processes for the preparation of compounds of the invention, and methods for their use as therapeutic agents.
Inventors:
CHRISTENSEN BURTON G (US)
FOLEY MICHAEL A (US)
GEORGES EVANGELINOS ASIMINA T (US)
LIU TAO (US)
PORTER JAMES R (US)
RIPKA AMY S (US)
ZHANG LINPING (US)
FOLEY MICHAEL A (US)
GEORGES EVANGELINOS ASIMINA T (US)
LIU TAO (US)
PORTER JAMES R (US)
RIPKA AMY S (US)
ZHANG LINPING (US)
Application Number:
PCT/US2005/021589
Publication Date:
November 23, 2006
Filing Date:
June 17, 2005
Export Citation:
Assignee:
INFINITY PHARMACEUTICALS INC (US)
CHRISTENSEN BURTON G (US)
FOLEY MICHAEL A (US)
GEORGES EVANGELINOS ASIMINA T (US)
LIU TAO (US)
PORTER JAMES R (US)
RIPKA AMY S (US)
ZHANG LINPING (US)
CHRISTENSEN BURTON G (US)
FOLEY MICHAEL A (US)
GEORGES EVANGELINOS ASIMINA T (US)
LIU TAO (US)
PORTER JAMES R (US)
RIPKA AMY S (US)
ZHANG LINPING (US)
International Classes:
C07D413/12
Foreign References:
| EP0191989A1 | 1986-08-27 | |||
| EP0250143A1 | 1987-12-23 |
Other References:
KANG, SUNG HO ET AL: "An asymmetric synthesis of a key intermediate to 1.beta.-methylcarbapenem antibiotics", TETRAHEDRON LETTERS , 36(37), 6713-16 CODEN: TELEAY; ISSN: 0040-4039, 1995, XP004027323
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