JAK KINASE MODULATING QUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF

Title:

JAK KINASE MODULATING QUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2010/099379

Kind Code:

A8

Abstract:

Provided herein are quinazoline compounds for treatment of JAK kinase mediated diseases, including JAK2 kinase-, JAK3 kinase- or TYK2 kinase-mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions. (I).

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Inventors:

ABRAHAM SUNNY (US)
CHAO QI (US)
HADD MICHAEL J (US)
HOLLADAY MARK W (US)
LIU GANG (US)
SETTI EDUARDO (US)

Application Number:

PCT/US2010/025500

Publication Date:

November 25, 2010

Filing Date:

February 26, 2010

Export Citation:

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Assignee:

AMBIT BIOSCIENCES CORP (US)
ABRAHAM SUNNY (US)
CHAO QI (US)
HADD MICHAEL J (US)
HOLLADAY MARK W (US)
LIU GANG (US)
SETTI EDUARDO (US)

International Classes:

C07D401/14; A61K31/517; A61P35/00; C07D403/12; C07D405/14

Attorney, Agent or Firm:

RIEGER, Dale, L. et al. (222 East 41st StreetNew York, NY, US)

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