Title:
LACTIC BACTERIUM HAVING AN EFFECT OF AMELIORATING METABOLIC SYNDROME
Document Type and Number:
WIPO Patent Application WO/2012/014971
Kind Code:
A1
Abstract:
Provided is a novel lactic bacterium capable of ameliorating metabolic syndrome by means of a novel screening method. Specifically disclosed are: a Lactobacillus which increases the production of adiponectin in 3T3-L1 cells and increases the production of an anti-inflammatory cytokine in bone-marrow-derived dendritic cells and/or macrophage; a culture of Lactobacillus; and a processed product of said culture. Also disclosed are a composition for foods and a pharmaceutical composition which contain the aforementioned Lactobacillus, culture, or processed product.
Inventors:
TOSHIMITSU TAKAYUKI (JP)
IKEGAMI SHUJI (JP)
ITOH HIROYUKI (JP)
IKEGAMI SHUJI (JP)
ITOH HIROYUKI (JP)
Application Number:
PCT/JP2011/067239
Publication Date:
February 02, 2012
Filing Date:
July 28, 2011
Export Citation:
Assignee:
MEIJI CO LTD (JP)
TOSHIMITSU TAKAYUKI (JP)
IKEGAMI SHUJI (JP)
ITOH HIROYUKI (JP)
TOSHIMITSU TAKAYUKI (JP)
IKEGAMI SHUJI (JP)
ITOH HIROYUKI (JP)
International Classes:
C12N1/20; A23L1/30; A23L33/115; A23L33/135; A61K35/74; A61K35/747; A61P3/04; A61P3/06; A61P3/10; A61P43/00; C12R1/25
Foreign References:
| JP2008214253A | 2008-09-18 |
Other References:
AIRO TATEGAKI: "Ko-Tonyobyo Koka o Yushita Nyusankin", NIPPON NOGEI KAGAKUKAI TAIKAI KOEN YOSHISHU, vol. 2008, 2008, pages 152
WANG, B ET AL.: "Isolation of adhesive strains and evaluation of the colonization and immune response by Lactobacillus plantarum L2 in the rat gastrointestinal tract.", INT J FOOD MICROBIOL., vol. 132, no. 1, 1 June 2009 (2009-06-01), pages 59 - 66, XP026094586, DOI: doi:10.1016/j.ijfoodmicro.2009.03.016
DIAZ-ROPERO, MP ET AL.: "Two Lactobacillus strains, isolated from breast milk, differently modulate the immune response.", J APPL MICROBIOL., vol. 102, no. 2, February 2007 (2007-02-01), pages 337 - 343
WANG, B ET AL.: "Isolation of adhesive strains and evaluation of the colonization and immune response by Lactobacillus plantarum L2 in the rat gastrointestinal tract.", INT J FOOD MICROBIOL., vol. 132, no. 1, 1 June 2009 (2009-06-01), pages 59 - 66, XP026094586, DOI: doi:10.1016/j.ijfoodmicro.2009.03.016
DIAZ-ROPERO, MP ET AL.: "Two Lactobacillus strains, isolated from breast milk, differently modulate the immune response.", J APPL MICROBIOL., vol. 102, no. 2, February 2007 (2007-02-01), pages 337 - 343
Attorney, Agent or Firm:
KUZUWA, Kiyoshi (JP)
Seiji Kuzuwa (JP)
Seiji Kuzuwa (JP)
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Claims:
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