Title:
LATERAL FLOW ANALYSIS STRIP AND MOLECULAR DIAGNOSTIC METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2021/187791
Kind Code:
A1
Abstract:
Disclosed are a lateral flow analysis strip and a molecular diagnostic method using same. The lateral flow analysis strip may comprise: a sample pad (100) into which a sample including at least one of a tag-labeled amplicon and a tag-labeled amplicon precursor is to be introduced; a conjugate pad (200) including a conjugate (C1) which has an indicator and a detector bound to the surface of the indicator and to which the conjugate (C1) is non-fixedly adsorbed; a test pad (300) including a test line (310) to which a first captor is fixed; a control pad (400) including a control line (410) to which a second captor is fixed; and an absorption pad (500). The lateral flow analysis strip of the present invention can detect an amplicon, such as a nucleic acid, amplified using an amplicon precursor such as a primer or dNTP, labeled with one type of tag, and can directly determine a result with the naked eye. In addition, the lateral flow analysis strip advantageously has a high sensitivity by using a tag having a strong binding force, a captor binding to the tag, a detector, and a captor binding to the detector. Further, the lateral flow analysis strip has a reproducible and stable effect by using a tag having a certain binding force, a captor binding to the tag, a detector, and a captor binding to the detector.
Inventors:
LEE BYUNG HWAN (KR)
KIM SE JIN (KR)
KIM DAMI (KR)
KIM SE JIN (KR)
KIM DAMI (KR)
Application Number:
PCT/KR2021/002898
Publication Date:
September 23, 2021
Filing Date:
March 10, 2021
Export Citation:
Assignee:
PHILMEDI CO LTD (KR)
International Classes:
C12Q1/70; G01N33/543
Foreign References:
| KR20180056343A | 2018-05-28 | |||
| KR20180081445A | 2018-07-16 | |||
| CN107012229A | 2017-08-04 | |||
| KR20170139157A | 2017-12-18 |
Other References:
BECHERER, LISA ET AL.: "Loop-mediated isothermal amplification (LAMP) - review and classification of methods for sequence-specific detection", ANALYTICAL METHODS, vol. 12, 9 January 2020 (2020-01-09), pages 717 - 746, XP055772674, DOI: 10.1039/C9AY02246E
See also references of EP 3954785A4
See also references of EP 3954785A4
Attorney, Agent or Firm:
LEE, Soo Yeol (KR)
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