Title:
LIGHT FILTERS USING THE OXIDATIVE POLYMERIZATION PRODUCT OF 3-HYDROXYKYNURENINE (3-OHKYN)
Document Type and Number:
WIPO Patent Application WO2005019874
Kind Code:
A3
Abstract:
The present invention is directed to a transparent medium incorporating the oxidative polymerization product of 3 -hydroxykynurenine, a synthetic version of the yellow-to-brown pigment that occurs in the ocular crystalline lens with age. Because this coloration in the ocular lens is believed to offer photoprotection to 6 the retina, it may represent an ideal sun lens filter with an optical transmission spectrum that is compatible with the psychophysical and neurophysiological characteristics of the vision system.
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Inventors:
GALLAS JAMES (US)
Application Number:
PCT/US2004/026961
Publication Date:
June 16, 2005
Filing Date:
August 19, 2004
Export Citation:
Assignee:
PHOTOPROTECTIVE TECHN INC (US)
GALLAS JAMES (US)
GALLAS JAMES (US)
International Classes:
G02B1/04; G02B5/22; G02C7/10; (IPC1-7): G02B5/22
Foreign References:
| US5187207A | 1993-02-16 |
Other References:
AQUILINA J.A. ET AL.: "Polypeptide modification and cross-linking by oxidized 3-hydroxykynumerine", BIOCHEMISTRY, vol. 39, no. 51, 26 December 2000 (2000-12-26), pages 16176 - 16184, XP002985573
TAYLOR L.M. ET AL.: "UV filter instability: consequences for the human lens", EXP. EYE RES., vol. 75, 2002, pages 165 - 175, XP002985574
TAYLOR L.M. ET AL.: "UV filter instability: consequences for the human lens", EXP. EYE RES., vol. 75, 2002, pages 165 - 175, XP002985574
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