Title:
LIPID COMPOUND AND COMPOSITION FOR DELIVERY OF ACTIVE SUBSTANCE
Document Type and Number:
WIPO Patent Application WO/2024/106781
Kind Code:
A1
Abstract:
The present invention relates to a novel lipid compound and a lipid nanoparticle (LNP) composition containing same. The lipid compound according to the present invention can either directly or indirectly bind to and surround an active substance through multivalent interactions, thereby increasing the structural stability of the active substance. In addition, when administered in vivo, the lipid nanoparticle composition containing the lipid compound significantly enhances the delivery efficiency into cells and the activity of the active substance, and thus can be useful for the treatment and prevention of diseases.
Inventors:
KIM YOONKYUNG (KR)
JEON HAE-GEUN (KR)
JUNG HYE-YOUN (KR)
HO VIET CUONG (KR)
LEE JI YOON (KR)
JEON HAE-GEUN (KR)
JUNG HYE-YOUN (KR)
HO VIET CUONG (KR)
LEE JI YOON (KR)
Application Number:
PCT/KR2023/016429
Publication Date:
May 23, 2024
Filing Date:
October 20, 2023
Export Citation:
Assignee:
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
International Classes:
C07C275/32; A61K9/51; C07C335/08; C07D207/337; C07D209/18; C07D233/90; C07D239/47; C07D239/52; C07D473/30; C07D473/34
Domestic Patent References:
| WO2021226597A2 | 2021-11-11 | |||
| WO2020061284A1 | 2020-03-26 | |||
| WO2018232120A1 | 2018-12-20 |
Foreign References:
| KR20190132405A | 2019-11-27 | |||
| CN113185421A | 2021-07-30 |
Attorney, Agent or Firm:
THEWAVE IP LAW FIRM (KR)
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