Title:
LIPID PEROXIDE-LOWERING COMPOSITIONS
Document Type and Number:
WIPO Patent Application WO/2002/038151
Kind Code:
A1
Abstract:
Compositions excellent in lowering lipid peroxides in the blood are provided. More particularly speaking, compositions for lowering lipid peroxides in the blood which contain pravastatin together with at least one substance selected from the group consisting of taurine, panthethine and inositol hexanicotinate. Use of these compositions makes it possible to provide excellent preventives or remedies capable of lowering the concentration of lipid peroxides in the blood which show effects of injuring vascular endothelial cells, accelerating platelet aggregation, forming foam cells, etc.
Inventors:
OHSAWA TSUNEOKI (JP)
TAKAGI IKUO (JP)
SHIMIZU IPPEI (JP)
KONDO TATSUHITO (JP)
NAKAYAMA MASATO (JP)
TORIZUMI YASUHIRO (JP)
TAKAGI IKUO (JP)
SHIMIZU IPPEI (JP)
KONDO TATSUHITO (JP)
NAKAYAMA MASATO (JP)
TORIZUMI YASUHIRO (JP)
Application Number:
PCT/JP2001/009662
Publication Date:
May 16, 2002
Filing Date:
November 05, 2001
Export Citation:
Assignee:
SANKYO CO (JP)
OHSAWA TSUNEOKI (JP)
TAKAGI IKUO (JP)
SHIMIZU IPPEI (JP)
KONDO TATSUHITO (JP)
NAKAYAMA MASATO (JP)
TORIZUMI YASUHIRO (JP)
OHSAWA TSUNEOKI (JP)
TAKAGI IKUO (JP)
SHIMIZU IPPEI (JP)
KONDO TATSUHITO (JP)
NAKAYAMA MASATO (JP)
TORIZUMI YASUHIRO (JP)
International Classes:
A61K31/16; A61K31/195; A61K31/22; A61K31/455; A61K31/465; A61P3/00; A61P43/00; (IPC1-7): A61K31/22; A61K31/16; A61K31/185; A61K31/455; A61P3/00; A61P43/00
Domestic Patent References:
| WO1999006035A2 | 1999-02-11 |
Other References:
DATABASE CAPLUS [online] AMERICAN CHEMICAL SOCIETY (ACS), (COLUMBUS, OHIO, USA); SALABERT-SALVADOR M.T. ET AL.: "QSAR relations from molecular connectivity of various physicochemical and pharmacological properties of a group of hypolipemic drugs", XP002907776, accession no. STN Database accession no. 122:305890
Attorney, Agent or Firm:
Ohno, Akio c/o SANKYO COMPANY (LIMITED 2-58 Hiromachi 1-chome Shinagawa-ku, Tokyo, JP)
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